The George Knox Roth Collection (1959-1980) consists of newspaper clippings (including photocopies), magazine articles, newsletters, technical reports and publications, correspondence, notes, and photographs relating to the Atomic Energy Commission, the environmental impact of nuclear testing in Nevada, Nevada mining, Airwest and the Hughes Airport, and other aspects of Howard Hughes’ Nevada operations. The George Knox Roth Collection also includes correspondence and expense reports related to his own company, General Research Consultants.

The William Hillman Shockley Photograph Collection (1875-1925, 1951) contains black-and-white photographs documenting mining operations at the Mount Diablo Mine and Millworks in Candelaria, Nevada. It also includes photographs of nearby operations including the Northern Belle Mine and the Princess Mill. The collection contains photographs of Shockley, his son, William Bradford Shockley, as an infant, as well as images of Shockley’s brothers, Walter A. Shockley and George Shockley.

The Bob McCaffery Collection on the Save the Hughes Flying Boat Campaign (1980-1983) documents efforts by activists to preserve the plane from destruction and its subsequent acquisition by the Aero Club of Southern California in 1980. The collection contains photographs and newspaper clippings about the Hughes H-4 Hercules flying boat nicknamed the "Spruce Goose" from the 1980s.

The Sadie and Hampton George Papers (1874-1948) consist primarily of the incoming and outgoing correspondence of Sadie Kiel George and her husband, Hampton George, regarding proposed land and mineral rights sales. The collection also includes some personal correspondence, and two of the most significant letters in the collection deal with the deaths of brothers William and Edward Kiel, Sadie's uncles, who were found dead at the Kiel Ranch in October 1900. Also included in the collection are receipts, cancelled checks, tax notices, mining claims, and land deeds.