The Edith Giles Barcus Family Photograph Collection (approximately 1878-1954) consists of black-and-white photographic prints and negatives, as well as postcards and photograph albums. The images depict locations in Nevada including Las Vegas, Goldfield, Searchlight, and Tonopah, in addition to locations in Arizona, California, Colorado, Massachusetts, Utah, and Mexico. Also included are images of family, friends, and associates of the Giles Barcus family. The albums contain photographs depicting the Giles family as they traveled through the southwest United States and Mexico, as well as postcards from prominent locations in the southwestern United States.

The Nevada Test Site Oral History Project Records (approximately 1950-2008) consist of oral histories collected by University of Nevada, Las Vegas Department of History for the Nevada Test Site Oral History Project. The collection includes digital audio recordings of interviews, print and digital transcripts, and a small selection of digital video recordings. Some interviews have also been supplemented with photographs, letters, scientific articles, brochures, news clippings and ephemera about the Nevada Test Site.

The Margo Mansergh Papers (approximately 1920-2010) document the life of former showgirl and dancer Margaret "Margo" Mansergh Tomaszewski. Materials include photographs of Margo modeling, backstage at various shows, portraits, and personal family photographs as well as programs from her international career performing in the Lido de Paris and Pigalle Nightclub in London, as well as a number of shows in Las Vegas, Nevada, such as Vive Les Girls, Casino de Paris, Minsky's Burlesque, and Lido de Paris at the Stardust. The collection contains materials from Mansergh's modeling career, including photographs, book covers, and images of her as an extra in films. Digital images from the closing Stardust performance and an event for Miss Bluebell are also found in the collection.

The History of Nursing in Southern Nevada Oral History Project Records (1965-2014) are comprised of material related to a volunteer project initiative at the University of Nevada, Las Vegas School of Nursing to conduct oral history interviews with nurses who have practiced in Southern Nevada. The collection contains subject files related to the project, as well as audio, video, and transcript files for the interviews. The collection also includes general information on nursing in Southern Nevada such as research papers and documents from the Nevada Nurses Association.

The Syphus-Bunker Papers date from 1891 to 1994, with the majority of the collection consisting of correspondence between Mary Etta Syphus and John Mathieson Bunker from 1891 to 1895. The collection also contains correspondence from friends and relatives, and documentation related to Mary Etta Syphus' attendance at Brigham Young Academy Church Normal Training School. Other materials include family history information and two color photographs of family homes. The collection also includes typed transcripts of the correspondence.

The Nevada Mining Collection is comprised of records that document mining and mines in Nevada from 1842 to 1966. The majority of the collection includes records of various mines and mining companies located in the Esmeralda, Lincoln, Clark, White Pine, and Nye counties, dating from 1900 to 1928. The collection includes financial, administrative, and business related records; photographs of miners, mining camps, and towns; correspondence; maps; newspaper clippings, pamphlets, newsletters, and booklets.