The Colorado River Commission of Nevada Reference Library Collection (1922-2000) documents the history of the Colorado River Commission (CRC) and is predominately comprised of books, briefs, memoranda, motions, exhibits, and other documents pertaining to the Arizona v. California litigation occurring between 1931 and 2000. The collection also contains meeting minutes, correspondence, budgets, reports, and other work files relating to the CRC. The CRC, located in Las Vegas, Nevada, is responsible for managing and protecting Nevada’s Colorado River water and power resources.

The Sandstone Ranch Collection is comprised of bank statements, letters, correspondence, and photographs relating to the Wilson family from 1907 to 1941. The collection includes information about the financial aspect of the Wilson Ranch, later renamed the Sandstone Ranch, located outside of Las Vegas, Nevada. The collection also includes information about the personal lives of those working on the including contracts about grazing cattle, selling cattle, and appropriation of water.

The Byrd Wall Sawyer Collection primarily consists of Byrd's research files on Nevada from 1930 to 1970. The materials concentrate on her monograph, "Nevada Nomads," as well as her co-authored textbook, "Here is Nevada." The collection also includes speeches, journal articles, memos, research note cards and papers, correspondence, informational booklets and pamphlets, maps, photographs, audiovisual materials, and newspaper articles and clippings.

The Pueblo Grande de Nevada Manuscript Collection (1924-1983) contains journal articles, photocopies of artifact inventories, reports, correspondence, and field notes related to the Pueblo Grande de Nevada archaeological site located in the Overton Valley of Southern Nevada. The bulk of the materials are related to Mark R. Harrington's archaeological reports, journal articles, and data from sites throughout the Overton and Moapa valleys. The collection also includes materials related to the Boulder Dam Park Museum (Lost City Museum of Archaeology) located in Overton, Nevada, which housed many of the artifacts and photographs from Harrington's archaeological sites.