The Nye County, Nevada Photograph Collection contains photographs from Nye County, Nevada from 1880 to 1990. The collection includes a wide variety of photographs that document the activities, landmarks, geographical features, towns, ranches, and families of Nye County. The collection covers the areas of Amargosa Valley, Ash Meadows, Beatty, Duckwater, Gabbs, Goldfield, Kawich Mountains, Manhattan, Pahrump, Round Mountain, Rhyolite, Smoky Valley, Springdale, Tecopa, Tonopah, and Twin Springs. The activities documented include mining, prospecting, herding animals, schooling, ranching, building construction, railroad construction, and hunting and fishing.

The Thomas J. Hickey Photograph Collection (1987-1989) contains color and black-and-white photographic prints of Thomas J. Hickey during his tenure as a Nevada State Senator. The collection also includes photographic prints of the Sparks, Nevada train yard and the Home of the Good Shepard church in Las Vegas, Nevada.

The James "Dee" Donithan Collection of Nevada Test Site Photographs (approximately 1970-1999) consist of 8x10 photographs depicting flowers, landscapes, wildlife, workers, work sites, and testing equipment at the Nevada Test Site. The photographs were printed by the Lawrence Livermore National Laboratory in Mercury, Nevada, and collected into a binder by James "Dee" Donithan.

The Reverend Donald M. Clark Photograph Collection (approximately 1965-1978) is comprised of black-and-white photographic prints and negatives. The bulk of the images portray Reverend Clark’s work with black communities in Las Vegas, Nevada and the Lake Tahoe area. Additional images depict Reverend Clark with various prominent individuals in the civil rights movement, including boxer Joe Frazier and American gospel singer Mahalia Jackson.

The George Kelly Ryan papers (1921-1971) contain correspondence inquiring about Octavius Decatur "O. D." Gass, newspaper clippings from 1929, handwritten recollections of the Gold Ranch by Laura Royce, and a San Pedro, Los Angeles and Salt Lake Railroad Company information, including information on wash-outs in Nevada.