The Frank Williams Papers on Early Nevada (1892-1946) consists of manuscripts written for the most part by Frank Williams, an early resident of Southern Nevada. The collection includes Williams' autobiography as well as histories of Goodsprings, Potosi Mine, Mesquite Valley, and the Yellow Pine Mining districts. Finally, this collection contains reports and material reflecting Frank Williams' two terms as University Regent (1909-1912 and 1923-1942) at the University of Nevada, Reno, and his four terms in the Nevada State Assembly.

The collection is comprised of the University of Nevada, Las Vegas (UNLV) Department of Anthropology and Ethnic Studies administrative records, memoranda, and correspondence dating from 1966 to 2006. The collection includes information about UNLV's department of Anthropology and Ethnic Studies from its inception at Nevada Southern University, its transition to UNLV, and research initiatives the department has undertaken.