The Kathy Eastland Papers (1972-2003) document Kathy Eastland's experiences working in Nevada brothels. Materials include ephemera and memorabilia collected by Eastland from various brothels in Nevada such as the Mustang Ranch, the Moonlite BunnyRanch, and Old Bridge Ranch. Included in the collection are brothel menus and photographs of Eastland and other sex workers socializing in the brothels. The collection also contains notes, research, and drafts of Eastland's manuscript Hell on Heels which describe her experience working in the brothel industry. Also included are prototypes of a game created by Eastland called "Brothelopoly" and some campaign materials about Jessi Winchester, a former brothel worker who ran for public office in Nevada. There is a small amount of materials about Joe Conforte, former owner of the Mustang Ranch, and some personal effects of Eastland including a motorcycle jacket and storage trunk.

The Alice Key Papers (1936-2004) consist of documents detailing Alice Key’s life and work in the African American community, historic preservation, and labor relations in Las Vegas, Nevada. Included in the collection are awards and certificates documenting Key’s achievements, invitations and programs to events, political and civic correspondence, and magazine and newspaper articles both about Key and written by her. The collection also contains photographs.

The Tomiyasu Family Photograph Collection (approximately 1908 to 1991) consists of black-and-white photographic prints of the Tomiyasu family and their farming business in southern Nevada.

The United States Department of Energy Photograph Collection on the Nevada Test Site contains photographs prints and negatives of nuclear testing, detonations, buildings, and wildlife on the Nevada Test Site (NTS) from 1945 to 1982. The photographs primarily depict nuclear explosions at the NTS and other test sites. The photographs also include preparations for nuclear tests, facilities at the NTS, and wildlife that live on the NTS.