The Las Vegas News Bureau Photograph Collection consists of black-and-white and color photographic prints, negatives, and slides depicting Las Vegas, Nevada from approximately 1940 to 1989. The images primarily depict hotels on the Strip in Las Vegas, Nevada, including Caesars Palace Las Vegas Hotel and Casino, the Flamingo Hotel & Casino, and the Desert Inn Hotel and Casino. Also included are images of the convention center in Las Vegas and Cashman Field, as well images of entertainers performing on the Las Vegas Strip. The collection consists entirely of photographic reproductions.

The Morrison Family Photograph Collection (1917-1933) consists of black-and-white and color photographic prints, negatives, and slides. The images primarily depict the Morrison family in Las Vegas, Nevada and the surrounding areas. Images portray youth activities in Nevada, including a local Boy Scouts Troop, Las Vegas High School students, Clark County High School students, as well as student activities at the University of Nevada, Reno. Also included are images of scenes around Las Vegas, including Mount Charleston, Little Falls, and the Colorado River prior to the Hoover Dam (Boulder Dam). Other images include Morrison family trips to California, Utah, Oregon, and Arizona.

The Harry Hayden Whiteley Photograph Collection (approximately 1940-1967) contains photographic prints and one photographic negative depicting buildings, people, and project locations associated with the Las Vegas, Nevada architect Harry Hayden Whiteley. There is also one album containing photographs of contemporary churches compiled by Whiteley between 1953 to 1958.

The Thomas McLaughlin Papers (1937-1985) are comprised of newspaper clippings, photographs, and correspondence about real estate, the Clark County Democratic Party, and local fraternal organizations, especially the Knights of Columbus and the Friendly Sons of Saint Patrick in Las Vegas, Nevada. Materials also include some clippings on McLaughlin's appointment as trustee of the Las Vegas Park Racetrack in 1955.

The Nancy Austin Papers (1966-1978) consist of newspaper clippings and photographs documenting the career of Las Vegas, Nevada entertainer Nancy Austin. The photographs document Austin’s entertainment career as well as other business ventures, including her own clothing line for plus-size women, called Pudgy Playmates.

William M. Stewart Correspondence is primarily comprised of handwritten letters addressed to U.S. Senator William Morris Stewart, between 1854 and 1872. Many of the letters were written during his first term in office. Also included is one document about the reappointment of a postmaster of Sutro, Nevada, and a manuscript telegram from Frances P. Hayes about the territorial organization and judicate district in Indian Territory.