Collection is comprised of correspondence, speeches, essays, meeting minutes, photographs, research materials, publications, press clippings, awards, and event programs (1941-2011) that document the life of Henry Schuster, and his work with his wife Anita. Materials are mainly related to the Holocaust and to Holocaust memory and survivor organizations (especially the Holocaust Survivor's Group of Southern Nevada, which the couple founded, and L’Œuvre de Secours aux Enfants). Genealogical information is also included, as well as records of Henry Schuster’s time in the U.S. Army and his studies at the Manhattan Technical Institute.

The collection is comprised of records of the San Pedro, Los Angeles & Salt Lake Railroad Company (1901-1976). The construction of this railroad led to the founding of Las Vegas, Nevada and the creation of the Empire Construction Company and Las Vegas Land and Water Company. The records document the company's operations and include correspondence and contracts relating to lots in the Las Vegas townsite, payments and accounts, invoices and other audit materials from 1905 to 1923. The collection also includes the records of the railroad agent at Arden Station, located ten miles south of the Las Vegas Station, which contain correspondence, ledgers, freight and way bills, shipping orders, and telegrams.