The Fred and Maurine Wilson Photograph Collection depicts the Wilson Family, events, and locations in Las Vegas, Nevada and the Southwestern United States from approximately 1860 to 1990. The photographs primarily depict early Las Vegas, including the Mormon Fort and Kiel Ranch; mines, towns, and railroads in Southern Nevada; the construction and planning of the Hoover (Boulder) Dam on the Colorado River; and the Wilson Family. The photographs also include prominent Las Vegas families such as the Park Family, aerial photographs of the city, landmarks on Fremont Street and downtown Las Vegas, and desert landscapes.

The Harmon Family Photograph Collection contains black-and-white and color photographic prints, negatives, postcards, and slides of the Harmon family in Las Vegas and Boulder City, Nevada between approximately 1900 and 1983. Las Vegas photographs depict the Harmon family in their home, at a ranch, and at Las Vegas High School. Boulder City photographs include a wedding and a view of Black Canyon, Nevada. Lastly, the collection also includes photographs of the Harmon family with various people, including the Wengert family and Howard Cannon, at receptions, ceremonies, and posing in front of Las Vegas buildings.