The collection is comprised of records of the San Pedro, Los Angeles & Salt Lake Railroad Company (1901-1976). The construction of this railroad led to the founding of Las Vegas, Nevada and the creation of the Empire Construction Company and Las Vegas Land and Water Company. The records document the company's operations and include correspondence and contracts relating to lots in the Las Vegas townsite, payments and accounts, invoices and other audit materials from 1905 to 1923. The collection also includes the records of the railroad agent at Arden Station, located ten miles south of the Las Vegas Station, which contain correspondence, ledgers, freight and way bills, shipping orders, and telegrams.

The Jean Ford Photograph Collection (1964-1977) contains black-and-white photographic prints, contact sheets, and transparencies of Nevada politician and activist Jean Ford. The collection includes photographs of Jean Ford with the Nevada State Park Commission and various Nevadan politicians; Ford lecturing and campaigning; and of the 1977 National Women's Conference in Houston, Texas.

The Blanche Zucker-Bozarth Papers document education advocate Blanche Zucker-Bozarth's volunteer work and activism in libraries, children's advocacy, and women’s clubs in Las Vegas, Nevada from 1963 to 2005. The collection includes records, newspaper clippings, and photographs from her political activism and fundraising initiatives in Southern Nevada. The collection also includes buttons, video tapes, and journal articles on child abuse prevention, as well as records from Zucker-Bozarth's term as president of the Mesquite Club in the 1980s.

The Nevada Desert Experience Records (1951-2009) are comprised of files from the anti-nuclear organization, the Nevada Desert Experience (NDE), as well as its predecessor, the Sagebrush Alliance, and those of earlier unincorporated protests at the Nevada Test Site (NTS). Materials include board of directors meeting minutes, financial records, scrapbooks, personnel records, event speeches, correspondence, newspaper clippings, cartoons and other artwork, newsletters, brochures, fliers, research files on nuclear issues and other anti-nuclear organizations, and congressional testimony. The records also contain audiovisual materials, photographic prints and slides, screenplays, manuscripts, and newspapers related to the NDE's media efforts.