The Albert S. Henderson Photograph Collection (1860s-1959) primarily contains black-and-white photographic prints of Albert S. Henderson and his family. Also included in the collection are photographic prints of Henderson during his tenure as a Nevada legislator and district judge. Other materials include postcards, negatives, and a tintype.

The John Nichols Photograph Collection (approximately 1930-1950) is comprised of black-and-white photographic prints depicting the western region of the United States including Southern Nevada, the Hoover Dam (then known as Boulder Dam), Lake Mead, and various desert landscapes. Photographs were collected by former Las Vegas and Boulder City, Nevada resident, John Nichols, who is a longtime art collector and gallery owner based in California. The collection includes some photographs taken by American photographer Glenn Davis who was known for photographing the Las Vegas Valley and the construction of the Hoover Dam.

The Archie C. Grant Photograph Collection (1914-1968) contains black-and-white photographs of Nevada politician Archie C. Grant. The materials include photographs of Grant with the Las Vegas Housing Authority at groundbreaking ceremonies, the University of Nevada Board of Regents, and with other Nevada politicians. Materials also contain early photographs of the University of Nevada, Las Vegas campus, including the dedication of Maude Frazier Hall.

The Nick Pratto Photograph Collection contains black-and-white photographic prints and negatives of Las Vegas, Nevada between approximately 1930 and 1950. The collection includes images of the 1940 and 1945 Helldorado parade, James Cashman Sr.'s Desert Love Buggy, and views of Gilmore Gas Station located at Fifth Street and Bonneville Avenue in 1934.

The Nye County, Nevada Photograph Collection contains photographs from Nye County, Nevada from 1880 to 1990. The collection includes a wide variety of photographs that document the activities, landmarks, geographical features, towns, ranches, and families of Nye County. The collection covers the areas of Amargosa Valley, Ash Meadows, Beatty, Duckwater, Gabbs, Goldfield, Kawich Mountains, Manhattan, Pahrump, Round Mountain, Rhyolite, Smoky Valley, Springdale, Tecopa, Tonopah, and Twin Springs. The activities documented include mining, prospecting, herding animals, schooling, ranching, building construction, railroad construction, and hunting and fishing.

The Marion Brooks Photograph Collection (approximately 1983-1989) contains one black-and-white photographic negative depicting Brooks with his family and associates, as well as three black-and-white photographic negatives of the Blue Diamond Mine in Clark County, Nevada. These negatives are reproductions of originals loaned to UNLV University Libraries Special Collection and Archives in 1983.

The Doris Hancock Photograph Collection (1882-1987) contains photographs of Las Vegas, Nevada educator Doris Hancock and her family. The collection includes images of Southern Nevada and surrounding areas, particularly the mining town of Rhyolite, Nevada, the Colorado River, the Hoover (Boulder) Dam, Red Rock Canyon, early Las Vegas, and Death Valley, California.