The Dorothy Ray Photograph Collection on Southern Nevada, approximately 1900-1946, depicts infrastructure in Caliente, Nevada in the early to mid-twentieth century. The collection also contains images of a flash flood that occurred in 1905 in Carp, Nevada and Stine, Nevada that washed away roads and railroad tracks. This collection provides historical documentation about early to mid-century Caliente, Nevada.

The Fanny’s Dress Shop Photographs (1930-1982) show one of Las Vegas’ premier women’s clothing stores. The collection includes images of Fanny Soss’ shop on Fremont Street, her store in the Flamingo Hotel, and Helldorado parades. Images include shop window displays.

The Q. B. Bush Papers are comprised of Q. B. Bush's personal papers dating from 1957 to 2018 and document Bush's work in Westside Las Vegas, Nevada casinos including the Moulin Rouge, Town Tavern, and the El Morocco. The collection also documents Bush's involvement with the Dealers Security Association and the association's effort to provide better working conditions for African American casino employees. Included are both original photographs and copies of photographs that document the African American casinos where Bush worked, as well as the Bush family at various events.

The Ned V. Bearden Sr. Photograph Collection contains black-and-white photographic prints and negatives of early Las Vegas, Nevada Fremont Street hotels, casinos, as well as Las Vegas businesses and residences between approximately 1940 to 1960. These photographs detail air conditioning units installations by Bearden throughout Las Vegas.

The Tonopah and Tidewater Railroad Records (1905-1977) contain correspondence, purchase requisitions, bills of lading, freight reports, and waybills. Also included are a ledger book, a rubber stamp, and a booklet, "Diagrams of Locomotives and Tenders." Incorporated in 1904, the Tonopah and Tidewater Railroad operated for 35 years, connecting Ludlow, California with Beatty, Nevada by way of Death Valley on the Santa Fe Railroad main line. The records are concentrated on the later years of the railroad from 1930 to 1940.

The Frank Williams Papers on Early Nevada (1892-1946) consists of manuscripts written for the most part by Frank Williams, an early resident of Southern Nevada. The collection includes Williams' autobiography as well as histories of Goodsprings, Potosi Mine, Mesquite Valley, and the Yellow Pine Mining districts. Finally, this collection contains reports and material reflecting Frank Williams' two terms as University Regent (1909-1912 and 1923-1942) at the University of Nevada, Reno, and his four terms in the Nevada State Assembly.