The Marie and James B. McMillan Photograph Collection (1900-1994) contains photographs of Marie and James B. McMillan and their families. The collection also includes photographs of their friends and professional associates, including journalist Hank Greenspun, Nevada civil rights pioneer J. David Hoggard, and entertainer Sammy Davis Jr. Marie McMillan is a former Las Vegas, Nevada flight instructor and one of the first women to work at the Nevada Test Site in Nye County, Nevada. James B. McMillan was the first African-American dentist to practice in Nevada, as well as a prominent Nevada civil rights leader.

The C. A. Earle Rinker Photograph Collection of Goldfield, Nevada (approximately 1900-1915) contains individual black-and-white photographic prints, photographic albums, black-and-white and tinted postcards, and photographic negatives that document the history of early twentieth century Goldfield, Nevada. The images include photographic prints of Goldfield and surrounding areas during its peak years of 1906-1910; postcards showing scenes of Goldfield, Tonopah, and other areas in central Nevada; and negatives that contain images of Rinker's family and homelife in Indiana and Illinois.

The Howard Hughes Public Relations Photograph Collection depicts the activities of businessman Howard Hughes from 1930 to 1950. The photographs primarily depict aircraft flown by Hughes or designed by the Hughes Aircraft Company, including the XF-11 reconnaissance plane, the HK-1 Hercules (or "Spruce Goose"), and the Hughes H-1 Racer. The photographs also depict celebrations following Hughes's circumnavigation flight in New York City, New York and Chicago, Illinois in 1938. Lastly, the photographs include Hughes testifying in front of the Senate Special Committee to Investigate the National Defense Program in 1947.