The Nan Doughty Family Collection dates from 1845 to 1993 and documents Doughty's personal and professional life. She collected correspondence and papers related to her extended family members including Sallie Bradford, Seymour Kimball Bradford, William Hillman Shockley, and May Bradford Shockley. The collection also includes papers from her father, Thorwald A. Siegfriedt, and her mother, Lou-vee Bradford Siegfried. Doughty used her family histories to write historical essays about early Nevada. The collection includes her professional papers as well as drafts and correspondence related to her writings.

The Minnie Perchetti Photograph Collection (approximately 1902-1959) consists of black-and-white photographic prints and negatives of Tonopah, Nevada and documents Tonopah in the first half of the 20th century. The photographs depict mines, events, buildings, people, and landscapes in Tonopah, Nevada. Included in the collection are photographs of the 1923 fire in Goldfield, Nevada.

The Tomiyasu Family Photograph Collection (approximately 1908 to 1991) consists of black-and-white photographic prints of the Tomiyasu family and their farming business in southern Nevada.

The Paris, France Show Programs Collection (1950-2000) is comprised of publicity print materials of the following cabaret music halls and burlesque clubs in Paris, France: Alcazar de Paris, Casino de Paris, Folies-Bergère, Le Lido de Paris, and Moulin Rouge Paris. The collection includes programs, advertising posters, fliers, long playing record albums, photograph slides, and restaurant menus. This material was formerly known as the International Show Programs Collection.

The Howard Schwartz Collection on Gaming documents the gaming industry in the United States from 1966 to 2010. The collection includes manuscripts, periodicals, newspaper articles, ephemera, profit and probability profiles and a report from the National Gambling Impact Study Commission.

The Coates Playing Cards Collection (1920s-1960s) consists of sixty-six decks of playing cards collected by Mrs. Phillip A. Coates. The collection includes promotional decks from various businesses, including the Southern Pacific Lines railroad and the Grace Line steamship company. The majority of the decks are of a narrower design to be used in playing canasta or bridge, with many being multi-deck sets.

The Donald Welch Photograph Collection (approximately 1961-1981) is comprised of photographs of various golf tournaments hosted at the Desert Inn Country Club in Las Vegas, Nevada collected by Welch throughout his career as the Desert Inn's head golf professional. In particular, the collection includes two photograph albums depicting the Ladies Professional Golf Association (LPGA) Sealy golf tournament in the early 1970s and a 25th anniversary Desert Inn Country Club commemorative photograph book from 1981.