The Wayne Cronister Photograph Collection depicts towns in Southern Nevada from 1905 to 1950. The photographs primarily depict Fremont Street in Las Vegas, Nevada and the construction of the Hoover (Boulder) Dam on the Colorado River. The photographs also include the Union Pacific Railroad Depot in Las Vegas, Nevada, the abandoned town of Rhyolite, Nevada, and a mining camp in El Dorado Canyon.

The Geneva Stark Merwin Photograph Collection features photographic prints and negatives of locations throughout Pahrump, Nevada between 1941 and 1942. Primary locations include a Pahrump school and Pahrump Ranch, as well as locations in local fields and mountains. The photographs capture candid scenes of people walking to school and feeding animals.

The Bill Willard Photograph Collection depicts Las Vegas, Nevada, hotels and casinos in Las Vegas, the Las Vegas Valley, and Laughlin, Nevada from 1905 to 1919 and from 1940 to 1999. The photographs primarily depict hotels and casinos in Las Vegas, including the Sahara Hotel, Circus Circus Hotel and Casino, MGM Grand Las Vegas Hotel and Casino, Caesars Palace, Flamingo Hotel, and the Aladdin Hotel. The photographs also depict students at Nevada Southern University (predecessor of the University of Nevada, Las Vegas), the city of Las Vegas, industrial plants in Henderson and Apex, Nevada, and events in Laughlin, Nevada.

The Georgia Lewis Photograph Collection contains black-and-white photographic prints and negatives primarily depicting Kyle Ranch, also known as Boulderado Ranch and Taylor Ranch, between approximately 1900 and 1950. The collection also features locations throughout Nevada such as Sloan, Panaca, Overton, and Indian Springs. Other images depict various individuals, including figures such as Grant Sawyer and J. Edgar Hoover, in Nevada locations and around the United States including Washington and Los Angeles, California.

The Thunderbird Plane Photograph Collection contains seven photographs of the Thunderbird Plane, its crew, its owners, and a photograph of Lake Mohave Resort from the 1960s to the 1970s. The Thunderbird Plane was owned by the Thunderbird Hotel and Casino in Las Vegas, Nevada.

The Nino Maurizi Photograph Collection consists of two black-and-white photographic prints and corresponding negatives of Nino Maurizi at the Mount Charleston Camp for the Las Vegas Army Air Field in 1943. Images depict Maurizi standing at the entrance of Mount Charleston Camp as well as inside the camp.

The Florence McClure Photograph Collection (approximately 1985-1997) consists of color photographic prints. Images show McClure and members of the Las Vegas, Nevada Community Action Against Rape (CAAR) organization that she co-founded with Sandi Petta in 1973. Also included are images of Nevada public figures and several travel images from China.