The Florence McClure Photograph Collection (approximately 1985-1997) consists of color photographic prints. Images show McClure and members of the Las Vegas, Nevada Community Action Against Rape (CAAR) organization that she co-founded with Sandi Petta in 1973. Also included are images of Nevada public figures and several travel images from China.

The Bruce Carlson Photograph Collection (approximately 2000-2009) consists of digital reproductions of Francis and Neeley family photographs taken during the early 1900s throughout Southern Nevada. Notable locations include Pioche, Eagle Valley, and Spring Valley, Nevada. This collection consists entirely of digital surrogates.

The L. F. Manis Photographs contain photographic prints, photographic slides, and photographic negatives depicting Southern Nevada from approximately 1900 to 1969, with a bulk of the materials dating from 1930 to 1940. The photographs primarily depict the construction, dedication, and various parts of the Hoover (Boulder) Dam, including the dam's upstream and downstream faces, intake towers, spillways, bridges, crest, outlet works, visitors' accommodations, and powerhouse. The photographs also depict Lake Mead, the reservoir created by the Hoover Dam, and the Colorado River, which is dammed by the Hoover Dam. The photographs also include views of desert landscapes in the Southwestern United States, including in Nevada, Arizona, and Southern California. Also depicted in the photographs are the cities of Las Vegas, Nevada and Boulder City, Nevada, including prominent buildings like hotels, casinos, government buildings, and train depots.

The Beckley Family Photograph Collection (approximately 1891-1982) consists of black-and-white photographic prints and negatives and color photographic slides. The images depict the Beckley family, their businesses in southern Nevada, and Las Vegas, Nevada as the city developed during the first half of the twentieth century. Also included are images of airplanes at the first Las Vegas airport Anderson Field, later renamed Rockwell Field in 1925, Fremont Street in Las Vegas, and postcards of mining towns across southern Nevada.

The Ferron and Bracken Photograph Collection depicts Southern and Central Nevada and other western states from 1890 to 1961. The photographs primarily depict the development and growth of early Las Vegas, Nevada; mines and mining operations in Southern and Central Nevada; towns and mines in Nevada; and the Hoover (Boulder) Dam and the Colorado River.

The Frank F. Watts Photograph Collection (approximately 1940-1959) contains black-and-white photographic prints, negatives, and slides. The photographs were taken in and around the El Rancho Vegas Hotel and Casino in Las Vegas, Nevada and include publicity photographs, celebrity images, wedding photographs, and images of the hotel interior and exterior. Also included are images of the El Rancho's executives with national figures, including Eleanor Roosevelt and Walter Winchell. A few additional images depict the Hoover Dam (Boulder Dam) and Lake Mead.

The Leon Rockwell Photograph Collection (approximately 1850-1979) contains black-and-white photographic prints, negatives, and slides, as well as postcards and tintypes. The images portray the lives of the Rockwell family in southern Nevada, their travels throughout New York and the western United States, and their immediate and extended family members. Also included are images of the volunteer and early firefighters of Las Vegas, Nevada, the Rockwell's family cabin at Mount Charleston, Nevada, and the Rockwell family home in Las Vegas. Portions of the images are from the Rockwell family travels across Nevada, Utah, New Mexico, Arizona, and California and depict historic locations such as Cove Fort, Utah; Rhyolite, Nevada; and Pueblo Grande de Nevada.