The Wayne Cronister Photograph Collection depicts towns in Southern Nevada from 1905 to 1950. The photographs primarily depict Fremont Street in Las Vegas, Nevada and the construction of the Hoover (Boulder) Dam on the Colorado River. The photographs also include the Union Pacific Railroad Depot in Las Vegas, Nevada, the abandoned town of Rhyolite, Nevada, and a mining camp in El Dorado Canyon.

The Stanley Mitchell Photograph Collection (approximately 1900-1980) consists of black-and-white photographic prints. The images portray street scenes and residents from mining communities in Southern Nevada, including Beatty, Alamo, Goldfield, Nye County, Pioche, Carrara, Esmeralda County, and Belmont, Nevada. Other images include officials signing a water bond in Esmeralda County members of the Central Nevada Cattlemen’s Association, and the Little Oasis Market in Alamo.

The Schuyler Family Photograph Collection (1889-2024) contains documents, census record forms, photographic prints and negatives, and ephemera which document the history of the Schuyler, Cahlan, and related families. The collection contains photographic prints of Donald Schuyler Sr. and his wife, Freda Schuyler, at various events and places around Las Vegas, Nevada. Some of the images also include members of the Cahlan and Ullom families, noteably A. E. Cahlan and his wife, Ruth, who were prolific Las Vegan authors. Some items in this collection are digital surrogates. This collection was previously called the Donald Schuyler Jr. Photograph Collection.

The Mindy Toutounji Photograph Collection (approximately 1935-1990) consists of color and black-and-white photographic prints and negatives of hotels and casinos located in Las Vegas, Nevada and Reno, Nevada. The photographs depict interior and exterior views and employees. Photographs from the Desert Inn Country Club document golf tournaments held in the 1950s and 1960s. The properties depicted are Castaways Hotel and Casino, Desert Inn Hotel, El Rancho Vegas, Frontier Hotel, and the Silver Slipper Gambling Hall, all located in Las Vegas, Nevada. The collection also includes photographs of Harold’s Club in Reno, Nevada.

The Helen M. Shepp Photograph Collection contains photographs of community organizations, entertainers, and significant figures in Las Vegas, Nevada from 1950 to 1964. The collection includes photographs of the American Association of the United Nations, the Navy Mother's Club, and the Women's Democratic Club. The collection also includes photographs of Nevada politicians and entertainers.

The Robbins Family Photograph Collection is comprised of eighteen black-and-white photographic reprints and five postcards that depict the Robbins family in Goodsprings and Searchlight, Nevada from approximately 1907 to 1977.

The Hotel Last Frontier Photograph Collection contains photographic prints, negatives, and slides depicting scenes inside and outside the Hotel Last Frontier in Las Vegas, Nevada between approximately 1940 and 1969. The collection also includes photographs under its alternate names: the Last Frontier and the New Frontier Hotel and Casino.