The L. F. Manis Photographs contain photographic prints, photographic slides, and photographic negatives depicting Southern Nevada from approximately 1900 to 1969, with a bulk of the materials dating from 1930 to 1940. The photographs primarily depict the construction, dedication, and various parts of the Hoover (Boulder) Dam, including the dam's upstream and downstream faces, intake towers, spillways, bridges, crest, outlet works, visitors' accommodations, and powerhouse. The photographs also depict Lake Mead, the reservoir created by the Hoover Dam, and the Colorado River, which is dammed by the Hoover Dam. The photographs also include views of desert landscapes in the Southwestern United States, including in Nevada, Arizona, and Southern California. Also depicted in the photographs are the cities of Las Vegas, Nevada and Boulder City, Nevada, including prominent buildings like hotels, casinos, government buildings, and train depots.

The Edward G. Halligan Photograph Collection on the Nevada Test Site contains photographs of nuclear detonations at the Nevada Test Site from the 1960s. The photographs primarily depict aboveground nuclear explosions, but they also contain photographs of facilities, machinery, and personnel at the Nevada Test Site.

The Helen J. Stewart Photographs depict the Stewart Family from approximately 1860 to 1950. The photographs primarily depict Helen J. Stewart and her children as well as the Stewart Ranch (also know as the Las Vegas Ranch) in Southern Nevada. The photographs include the early Las Vegas, Nevada town site, landscapes of Southern Nevada and the American Southwest, mines and mining camps, railroads and railroad workers, the Las Vegas Fort (also known as the Old Mormon Fort), hotels and early businesses in Las Vegas, Native Americans and Native American artifacts, and postcards.

The Nevada Division of State Parks Photograph Collection (approximately 1910-1940) contains black-and-white photographic prints and some corresponding negatives that depict state parks and recreational areas throughout southern Nevada. The images also portray Lake Mead, Hoover Dam, Logandale, the Valley of Fire, and Mount Charleston as well as images of actors filming on location in southern Nevada.

The K. O. Knudson Photographs (approximately 1920-1969) depict the Las Vegas Grammar School and service, fraternal, and veterans organizations gathered by retired Las Vegas, Nevada school administrator and World War I veteran K. O. Knudson (also known as K. Oscar Knudson). The collection includes images of Knudson, Las Vegas Masonic Lodge members, American Legion members, and school dances. The photographs primarily feature Las Vegas, Nevada.

The Fayle Family Photographs depict the Fayle Family in Southern Nevada and California from 1888 to 1990. The photographs primarily include family photographs of Leonard Fayle, Anna Louise Trapnell Fayle, Leonard Fayle’s parents George Fayle and Jean Henderson Fayle, Leonard Fayle’s siblings George Arthur Fayle and Jean Nevada Fayle, and Leonard and Anna Fayle’s children Jane and Edward Fayle. The photographs also depict the Nevada towns of Las Vegas, Goodsprings, and Jean, including railroad operations, mining, milling, and hauling freight. The collection includes a leather-bound photograph album containing images of the Fayle Family and the Yount Family.

The George Laurence Ullom Photograph Collection (1915-1974) contains photographic prints and negatives created by Las Vegas, Nevada photographer George Laurence "Larry" Ullom. Larry owned and operated Ullom’s Desert Art Studio, which was located in Las Vegas, Nevada. The bulk of the collection consists of Ullom's wedding chapel photography. The collection also includes his photography work for the Bureau of Reclamation, the Agricultural Extension Service, and the Associated Press, Atlantic News, and Acme news bureaus.