The Yucca Mountain Site Characterization Office collection (1958-2001) was assembled through a joint effort between the Nuclear Regulatory Commission (NRC) and the James R. Dickinson Library, University of Nevada, Las Vegas (UNLV) to provide public access to documentation and correspondence about the proposed high-level radioactive waste geologic repository site near Yucca Mountain, Nevada. Materials include technical reports, contractor reports, public hearing transcripts, safety evaluation reports, environmental impact statements, emergency plans, inspection reports, licensee event reports, and general communications. The collection includes documents from several other government entities such as the Yucca Mountain Site Characterization Office, Department of Energy, Office of Civilian Radioactive Waste Management (OCRWM), Nevada Nuclear Waste Storage Investigations (NNWSI), United States Geological Survey (USGS), Sandia National Laboratories, Lawrence Livermore National Laboratory, and Los Alamos National Laboratory.

The Howard Hughes Public Relations Photograph Collection depicts the activities of businessman Howard Hughes from 1930 to 1950. The photographs primarily depict aircraft flown by Hughes or designed by the Hughes Aircraft Company, including the XF-11 reconnaissance plane, the HK-1 Hercules (or "Spruce Goose"), and the Hughes H-1 Racer. The photographs also depict celebrations following Hughes's circumnavigation flight in New York City, New York and Chicago, Illinois in 1938. Lastly, the photographs include Hughes testifying in front of the Senate Special Committee to Investigate the National Defense Program in 1947.