Collection is comprised of correspondence, speeches, essays, meeting minutes, photographs, research materials, publications, press clippings, awards, and event programs (1941-2011) that document the life of Henry Schuster, and his work with his wife Anita. Materials are mainly related to the Holocaust and to Holocaust memory and survivor organizations (especially the Holocaust Survivor's Group of Southern Nevada, which the couple founded, and L’Œuvre de Secours aux Enfants). Genealogical information is also included, as well as records of Henry Schuster’s time in the U.S. Army and his studies at the Manhattan Technical Institute.

The Jean Ford Photograph Collection (1964-1977) contains black-and-white photographic prints, contact sheets, and transparencies of Nevada politician and activist Jean Ford. The collection includes photographs of Jean Ford with the Nevada State Park Commission and various Nevadan politicians; Ford lecturing and campaigning; and of the 1977 National Women's Conference in Houston, Texas.

The Dorothy Dorothy papers (approximately 1913-1986) document the life of singer, songwriter, columnist, pilot, and farmer, Dorothy Dorothy. Materials contain genealogy records, correspondence, business and organizational records, local history, sheet music, artifacts, and two boxes of photographic prints. Also included are materials relating to her active involvement with animal rights campaigns.

The collection is comprised of records of the San Pedro, Los Angeles & Salt Lake Railroad Company (1901-1976). The construction of this railroad led to the founding of Las Vegas, Nevada and the creation of the Empire Construction Company and Las Vegas Land and Water Company. The records document the company's operations and include correspondence and contracts relating to lots in the Las Vegas townsite, payments and accounts, invoices and other audit materials from 1905 to 1923. The collection also includes the records of the railroad agent at Arden Station, located ten miles south of the Las Vegas Station, which contain correspondence, ledgers, freight and way bills, shipping orders, and telegrams.

The Bill Schafer Papers (1980-2018) contain personal and professional papers of Las Vegas, Nevada journalist and publisher, Bill Schafer, and photographs from various LGBTQIA+ related events in Las Vegas. The materials include files related to Schafer's work managing the Las Vegas Night Beat and Las Vegas Bugle publications. The collection contains copies of various LGBTQIA+ directories and photographs from events such as the Las Vegas Pride parade and the Gay and Lesbian Community Center of Southern Nevada's annual Honorarium. Also included are photographs and papers from Schafer's involvement with the Imperial Royal Sovereign Court of the Desert Empire, Inc.

The John Levy Lighting Productions, Inc. Records (approximately 1990-2022) contain correspondence, invoices, contracts, expense reports, newspaper and magazine clippings, photographs, slides, and digital files detailing the development of various projects primarily in Las Vegas, Nevada. The records also contain architectural lighting drawings, electrical schematics and design details, conceptual sketches, and artist renderings of projects in Las Vegas, throughout United States, and various international locations.

The Howard Hughes Professional and Aeronautical Photographs contain black-and-white photographs of businessman and entrepreneur Howard Hughes and his companies from 1916 to 1997. The photographs primarily depict Hughes alongside his aircraft, including the XF-11 prototype reconnaissance plane and the HK-1 Hercules, better known as the "Spruce Goose" or "Flying Boat." The photographs also cover the companies owned by Hughes, including Hughes Tool Company, Hughes Aircraft Company, Hughes Electronics Corporation, and RKO Pictures.