Collection is comprised of correspondence, speeches, essays, meeting minutes, photographs, research materials, publications, press clippings, awards, and event programs (1941-2011) that document the life of Henry Schuster, and his work with his wife Anita. Materials are mainly related to the Holocaust and to Holocaust memory and survivor organizations (especially the Holocaust Survivor's Group of Southern Nevada, which the couple founded, and L’Œuvre de Secours aux Enfants). Genealogical information is also included, as well as records of Henry Schuster’s time in the U.S. Army and his studies at the Manhattan Technical Institute.

The Pueblo Grande de Nevada Manuscript Collection (1924-1983) contains journal articles, photocopies of artifact inventories, reports, correspondence, and field notes related to the Pueblo Grande de Nevada archaeological site located in the Overton Valley of Southern Nevada. The bulk of the materials are related to Mark R. Harrington's archaeological reports, journal articles, and data from sites throughout the Overton and Moapa valleys. The collection also includes materials related to the Boulder Dam Park Museum (Lost City Museum of Archaeology) located in Overton, Nevada, which housed many of the artifacts and photographs from Harrington's archaeological sites.

The Claudine Williams Papers (1956-2009) contain awards, contracts, personal and business correspondence, newspaper clippings, and photographs pertaining to Las Vegas, Nevada businesswoman and philanthropist, Claudine Williams. The collection also includes extensive information on her hotel and gaming properties, including the Silver Slipper Gambling Hall, Holiday Casino, and Harrah's Hotel and Casino, as well as her honorary doctoral degree, medals, and audiovisual materials of interviews, news reports, and events.