The locations in Southern Nevada and the Southwestern United States photographs depict people in Southern Nevada and the Southwestern United States from approximately 1900 to 1975. The photographs include politicians and engineers investigating the Colorado River for the future sight of the Hoover (Boulder) Dam in Black Canyon; Hoover Dam workers and construction; the towns of Goodsprings, Beatty, and Indian Springs in Nevada; the Grand Canyon in Arizona; and Mount Charleston in Nevada. The items described include black-and-white photographic prints, postcards, and negatives; items listed are photographic prints unless otherwise specified.

The Southern and Central Nevada photographs depict locations in Southern and Central Nevada from 1890 to 1950. The photographs depict mining operations, mills, animal freight teams, the Colorado River, Euro-American settlers, Valley of Fire, and Native Americans. The photographs also depict the towns of Boulder City, Goodsprings, St. Thomas, Callville, and Moapa. The items described include black-and-white photographic prints, postcards, and negatives; items listed are photographic prints unless otherwise specified. Numbered items inside oversized boxes are photographs within scrapbooks and have been digitized.