The Mavis Eggle "Books as They Were Bought" collection provides a broad overview of printed material from the 1780s through 1949. Gathered by book collector Mavis Eggle, the collection serves as a social history of books, newspapers, and ephemera. Physical characteristics of the books include a variety of printer's marks, publishers' bindings, bookplates, and early subscription libraries. The collection's titles are a diverse and creative gathering of poetry, children' literature, religious texts, broadsides, newspapers, and popular fiction. Together, the items in the Mavis Eggle "Books as They Were Bought" collection illustrate changes in literature, printing and publishing, advertising, and book history over a time period of more than 170 years.

The UNLV Libraries Collection of Casino Promotional and Publicity Material (1966-2004) consists of clothing, promotional souvenirs, and gambling ephemera from various hotels and casinos throughout Las Vegas, Nevada. These items include hats, shirts, mugs, ash trays, drinking glasses, menus, buckets, keychains, keno supplies, and playing cards. The hotels include Caesar's Palace, Flamingo Hotel, Imperial Palace, Palace Station, Showboat, Castaways, Stardust, El Rancho, Sam's Town, Circus Circus, and Four Queens, in addition to others throughout Las Vegas.

The Cal McKinley Collection of Tune-Dex Cards spans from 1943 to 1950 and contains a collection of index cards called Tune-Dex Cards that provide the lyrics and melodies of popular tunes from the late 1940s.

The Yucca Mountain Site Characterization Office collection (1958-2001) was assembled through a joint effort between the Nuclear Regulatory Commission (NRC) and the James R. Dickinson Library, University of Nevada, Las Vegas (UNLV) to provide public access to documentation and correspondence about the proposed high-level radioactive waste geologic repository site near Yucca Mountain, Nevada. Materials include technical reports, contractor reports, public hearing transcripts, safety evaluation reports, environmental impact statements, emergency plans, inspection reports, licensee event reports, and general communications. The collection includes documents from several other government entities such as the Yucca Mountain Site Characterization Office, Department of Energy, Office of Civilian Radioactive Waste Management (OCRWM), Nevada Nuclear Waste Storage Investigations (NNWSI), United States Geological Survey (USGS), Sandia National Laboratories, Lawrence Livermore National Laboratory, and Los Alamos National Laboratory.

The Sue Fawn Chung Collection on Asians in Nevada (1963-2015) consists of materials collected by Dr. Sue Fawn Chung in the course of her research on the history of Asians in Nevada. The collection contains interviews, correspondence, and biographical materials primarily focusing on Chinese and Japanese residents in Nevada, but also includes other communities such as Filipinos and Koreans. Some materials are photocopies of original documents and photographs dating between 1913 and 1960.

The Anita Freeman Photograph Collection on Southern Nevada (1937-1972) primarily contains black-and-white negatives depicting locations in Southern Nevada, including the Hoover Dam, Lake Mead, and Mount Charleston. The collection also includes black-and-white negatives of the Helldorado Parade held in Las Vegas, Nevada, as well as landscapes in Arizona, such as the Grand Canyon.

The Nevada Southern University Land Foundation Collection (1961-1972) contains documents relating to the planning and expansion of the University of Nevada, Southern Regional Division (now University of Nevada, Las Vegas) campus in Las Vegas, Nevada. The collection contains development studies, reports, city maps, and correspondence.