The Pueblo Grande de Nevada Manuscript Collection (1924-1983) contains journal articles, photocopies of artifact inventories, reports, correspondence, and field notes related to the Pueblo Grande de Nevada archaeological site located in the Overton Valley of Southern Nevada. The bulk of the materials are related to Mark R. Harrington's archaeological reports, journal articles, and data from sites throughout the Overton and Moapa valleys. The collection also includes materials related to the Boulder Dam Park Museum (Lost City Museum of Archaeology) located in Overton, Nevada, which housed many of the artifacts and photographs from Harrington's archaeological sites.

The Elbert Edwards Photograph Collection contains photographs of Nevada from 1852 to 1991. The collection has a wide variety of photographs, including: white pioneers and settlers; early Nevada towns; Nevada politicians; early Las Vegas landmarks; Boulder City schools; petroglyphs from Nevada's indigenous populations; Lost City and Lake Mead; railroads; the Hoover Dam (Boulder Dam); Basic Magnesium Inc. in Henderson, Nevada; geographical features; the Edwards family; and photographs of Elbert Edwards's participation in the Las Vegas Education Association and the Rotary Club.

The United States Department of Energy Photograph Collection on the Nevada Test Site contains photographs prints and negatives of nuclear testing, detonations, buildings, and wildlife on the Nevada Test Site (NTS) from 1945 to 1982. The photographs primarily depict nuclear explosions at the NTS and other test sites. The photographs also include preparations for nuclear tests, facilities at the NTS, and wildlife that live on the NTS.

The Sands Hotel Photograph Collection depicts entertainers, celebrities, events, amenities, and staff at the Sands Hotel in Las Vegas, Nevada from approximately 1952 to 1980. The photographs primarily depict entertainers like Frank Sinatra, Dean Martin, and the Copa Girls performing in the Copa Room, the showroom of the Sands Hotel. The photographs also depict patrons gambling, events held in the Sands Hotel's ballrooms, banquets, the pool, rooms in the hotel, as well as Jack Entratter, the hotel'’s director of entertainment.

The Ruby Duncan Photograph Collection on Operation Life (1970s-1980s) is comprised primarily of photographic prints with some corresponding 35 mm negatives of Ruby Duncan and other Operation Life organizers, as well as important organization buildings. Materials include photographs of Ruby Duncan, Aldine Weems, Renee Diamond, and Jack Anderson in the original Operation Life Las Vegas, Nevada Operation Life headquarters and the regional office in San Francisco, California. Also pictured are other employees and beneficiaries of the organization at a Christmas Party.

The Vassili Sulich Photographs depict dancer and choreographer Vassili Sulich from 1950 to 2011. The photographs primarily depict Sulich dancing in ballets in France, Croatia, Germany, England, and the United States. The photographs also depict ballets choreographed or directed by Sulich at the Nevada Dance Theatre, which he founded in 1972 in Las Vegas, Nevada.

The Harold Stocker Photographs depict Harold Stocker and his family from 1850 to 1980. Materials include photographs of Harold Stocker, his parents, his siblings, and his extended family. Materials also include photographs of Harold Stocker's business interests such as the Northern Club in Las Vegas, Nevada, the Nevada Silica Sand Company in Overton, Nevada, and the Chief Hotel Court on Fremont Street in Las Vegas, Nevada. The collection also contains photographs of Stocker participating in Republican Party events in Nevada.