The Robert B. Griffith Collection (1928-1975) documents the work of Robert B. Griffith, an instrumental figure in the development of water resources in Las Vegas, Nevada, as well as the creation of McCarran International Airport and Nellis Air Force Base. The collection consists of Colorado River Commission papers, 1928 International Air Race documents, general correspondence, a feasibility study, an airport guide, American Legion papers, the memoirs of Alfred Merritt Smith, and death and burial records belonging to his father. The collection also includes slides from various countries, including the United States, Canada, Europe, Asia, and the Middle East.

The McCall Family Papers are comprised primarily of family photographs and correspondence from 1910-1970. The materials concentrate on Quannah McCall and his daughter, Connie McCall, both were well known dentists in Southern Nevada. The materials also contain letters, postcards, holiday cards, and birth, death, and marriage certificates, as well as school commencement announcements for family members.

The Hazel Baker Denton Photograph Collection (1910-1961) is comprised of photographic prints and one negative of the Denton family and friends, primarily taken in Nevada and Utah. Many photographs depict life in small Nevada towns, particularly Caliente. Photographs also depict Utah, Oregon, Washington D.C., and California, and unidentified desert and forest landscapes throughout the American West.

The Robert E. "Spud" Lake Photographs depict "Spud" Lake, his family, and Las Vegas, Nevada from 1905 to 1947. The photographs include the Las Vegas town site auction, Stewart (Kiel) Ranch, Clark County Courthouse, Eglington Ranch, Helldorado Parade, and Colorado River and the Hoover (Boulder) Dam. The photographs also depict a Las Vegas Chamber of Commerce luncheon honoring Las Vegas pioneers, the Gold Bar Club tent in Pahrump, Nevada, and Fremont Street in Las Vegas.