The Bill Willard Photograph Collection depicts Las Vegas, Nevada, hotels and casinos in Las Vegas, the Las Vegas Valley, and Laughlin, Nevada from 1905 to 1919 and from 1940 to 1999. The photographs primarily depict hotels and casinos in Las Vegas, including the Sahara Hotel, Circus Circus Hotel and Casino, MGM Grand Las Vegas Hotel and Casino, Caesars Palace, Flamingo Hotel, and the Aladdin Hotel. The photographs also depict students at Nevada Southern University (predecessor of the University of Nevada, Las Vegas), the city of Las Vegas, industrial plants in Henderson and Apex, Nevada, and events in Laughlin, Nevada.

This collection is comprised of publicity photographs of Howard Hughes and his aircrafts, from approximately the 1940s to the 1950s, that were compiled by David Rea, former pilot for Hughes Aircraft Company. This collection also includes clippings and technical drawings of Hughes aircrafts.

The Mike Smith Editorial Cartoons (1980-2023) contain editorial cartoons created by Las Vegas, Nevada based cartoonist Mike Smith for the Las Vegas Sun newspaper. Materials include Smith's editorial cartoons on NASCAR and a copy of his 2003 book StockcarToons. The collection also includes Smith's personal sketchbooks and letters from fans.