The Yucca Mountain Environmental Safety Collection (1970-2011) consists of reports and impact studies collected by Clark County's Nuclear Waste Division library for documenting Yucca Mountain's potential health and safety risks to Southern Nevada. The reports contain documents pertaining to potential environmental, health, financial, and safety risks from the Yucca Mountain Nuclear Waste Repository, which is located in Nye County, Nevada. The collection contains scientific and social studies in support of and opposition to the site. The bulk of the collection includes licensing reports, site selection studies, and impact studies from transporting, storing, and handling radioactive waste and spent nuclear fuel.

The collection is comprised of architectural drawings (1952-1997) completed by American architect, Ethan Jennings Jr. and/or his architectural firm, Ethan Jennings Jr., AIA, CSI and includes Jenning's work from the firm of John Badgley, AIA, where Ethan Jennings Jr. worked in Southern California during the 1950s, as well as work Jenning's completed with Americo Inc., and Tolosa Group. The collection contains 217 sets of drawings, 6 boxes of project records, and 8 flat files of oversized material from over 200 different projects primarily located in California with some projects located in the Las Vegas area. The materials feature hand-drawn architectural drawings, ranging from preliminary sketches to construction documents. The drawings also contain work from consultants, engineers, and other architects who collaborated on the development of the various projects. The drawings include: commercial, industrial, professional, civic, residential, and religious buildings of varying scales, such as libraries, apartments, warehouses, office developments, schools, military buildings, churches, and custom single-family homes located throughout California and Las Vegas. The drawings also include a number of additions, remodels, and renovations. The collection also contains project records like structural calculations and drawings, project manuals and specifications, bid documents, and professional correspondence.

The Alpha Kappa Alpha Sorority, Incorporated, Theta Theta Omega (AKA TTO) Chapter records (1965-2020) are comprised of organizational records, conference programs, digitized copies of the chapter's scrapbooks, and copies of Ivy Leaf, the organization’s national newsletter. The records include chapter and committee agendas and meeting minutes, Far Western Regional Conference reports, and fliers for events hosted by AKA TTO. Also included are archived web captures of AKA TTO's website and digital audio and video files for the chapter's oral history project interviewing Charter, Golden, and Silver members from 2019 to 2020.

The Sister Klaryta Antoszewska Photograph Collection (1977-1991) consists of photographic slides that depict various Nevada, United States, and international nuclear test protests. The collection includes images of Sister Klaryta Antoszewska and Sister Rosemary Lynch, as well as images of the Lenten Desert Experience and numerous protests at the Nevada Test Site. Also included are images of nuclear testing, soldiers, and anti-nuclear testing promotional materials.

The Thomas Hickey Political Papers (1964-1996) contain the professional files of Hickey’s career as a Nevada State Assemblyman and Senator. Materials include constituent correspondence, voting records, memoranda, newspaper clippings, bills, and research documentation on topics such as the Yucca Mountain Nuclear Waste Repository, the Equal Rights Amendment (ERA), education, health, prisons, finance, and Nevada infrastructure. The collection highlights Hickey’s role on committees including finance, transportation, government affairs, and ways and means.