The Elbert Edwards Photograph Collection contains photographs of Nevada from 1852 to 1991. The collection has a wide variety of photographs, including: white pioneers and settlers; early Nevada towns; Nevada politicians; early Las Vegas landmarks; Boulder City schools; petroglyphs from Nevada's indigenous populations; Lost City and Lake Mead; railroads; the Hoover Dam (Boulder Dam); Basic Magnesium Inc. in Henderson, Nevada; geographical features; the Edwards family; and photographs of Elbert Edwards's participation in the Las Vegas Education Association and the Rotary Club.

The Georgia Lewis Photograph Collection contains black-and-white photographic prints and negatives primarily depicting Kyle Ranch, also known as Boulderado Ranch and Taylor Ranch, between approximately 1900 and 1950. The collection also features locations throughout Nevada such as Sloan, Panaca, Overton, and Indian Springs. Other images depict various individuals, including figures such as Grant Sawyer and J. Edgar Hoover, in Nevada locations and around the United States including Washington and Los Angeles, California.

The Beckley Family Photograph Collection (approximately 1891-1982) consists of black-and-white photographic prints and negatives and color photographic slides. The images depict the Beckley family, their businesses in southern Nevada, and Las Vegas, Nevada as the city developed during the first half of the twentieth century. Also included are images of airplanes at the first Las Vegas airport Anderson Field, later renamed Rockwell Field in 1925, Fremont Street in Las Vegas, and postcards of mining towns across southern Nevada.

The El Rancho Vegas Collection (1953-1961) is comprised of materials and memorabilia from the El Rancho Vegas Hotel collected by former hotel controller, Frank Watts. Records include financial documents including endorsed checks to performers at the resort. Other items included unused stationary, copies of the menu, and memorabilia from the hotel. The collection also contains a bathmat, hangers, and a drinking glass from the hotel.

The George Petri Collection (approximately 1977-2010) contains food and beverage management manuals and employee instructional documentation from various resorts in Las Vegas, Nevada including Empress Casino, Harrah's Entertainment, Luxor, and Station Casinos. The materials were collected by George Petri, who was a Maître d'hôtel at the Regency Room restaurant at the Sands Hotel and Casino and also worked at other resorts in Las Vegas. Materials also include artifacts such as silver plated dinnerware from the Regency Room and various menus and memorabilia from the Sands Hotel over the years.

The William Barak Collection (approximately 1962-1989) contains photographs of Barak and colleagues while working E.G. & G. at the Nevada Test Site and in Alaska from the NERVA (Nuclear Rocket) Division and the last two tests in Amchitka (Milrow and Cannikin). The collection also contains numerous government publications, manuals, and maps relating to Barak's work.

The John Pappas Photograph Collection is comprised of four black-and-white photographic reprints, taken from between 1930 to 1949 and reprinted from between 1999 to 2005, that depict employees from the White Spot Cafe in Las Vegas, Nevada being paid in silver dollars by the owner, John Pappas.