The Ruby Duncan Photograph Collection on Operation Life (1970s-1980s) is comprised primarily of photographic prints with some corresponding 35 mm negatives of Ruby Duncan and other Operation Life organizers, as well as important organization buildings. Materials include photographs of Ruby Duncan, Aldine Weems, Renee Diamond, and Jack Anderson in the original Operation Life Las Vegas, Nevada Operation Life headquarters and the regional office in San Francisco, California. Also pictured are other employees and beneficiaries of the organization at a Christmas Party.

The Vassili Sulich Photographs depict dancer and choreographer Vassili Sulich from 1950 to 2011. The photographs primarily depict Sulich dancing in ballets in France, Croatia, Germany, England, and the United States. The photographs also depict ballets choreographed or directed by Sulich at the Nevada Dance Theatre, which he founded in 1972 in Las Vegas, Nevada.

The Kathy Eastland Papers (1972-2003) document Kathy Eastland's experiences working in Nevada brothels. Materials include ephemera and memorabilia collected by Eastland from various brothels in Nevada such as the Mustang Ranch, the Moonlite BunnyRanch, and Old Bridge Ranch. Included in the collection are brothel menus and photographs of Eastland and other sex workers socializing in the brothels. The collection also contains notes, research, and drafts of Eastland's manuscript Hell on Heels which describe her experience working in the brothel industry. Also included are prototypes of a game created by Eastland called "Brothelopoly" and some campaign materials about Jessi Winchester, a former brothel worker who ran for public office in Nevada. There is a small amount of materials about Joe Conforte, former owner of the Mustang Ranch, and some personal effects of Eastland including a motorcycle jacket and storage trunk.

The collection is comprised of records of the San Pedro, Los Angeles & Salt Lake Railroad Company (1901-1976). The construction of this railroad led to the founding of Las Vegas, Nevada and the creation of the Empire Construction Company and Las Vegas Land and Water Company. The records document the company's operations and include correspondence and contracts relating to lots in the Las Vegas townsite, payments and accounts, invoices and other audit materials from 1905 to 1923. The collection also includes the records of the railroad agent at Arden Station, located ten miles south of the Las Vegas Station, which contain correspondence, ledgers, freight and way bills, shipping orders, and telegrams.

The Harold Stocker Photographs depict Harold Stocker and his family from 1850 to 1980. Materials include photographs of Harold Stocker, his parents, his siblings, and his extended family. Materials also include photographs of Harold Stocker's business interests such as the Northern Club in Las Vegas, Nevada, the Nevada Silica Sand Company in Overton, Nevada, and the Chief Hotel Court on Fremont Street in Las Vegas, Nevada. The collection also contains photographs of Stocker participating in Republican Party events in Nevada.

The Las Vegas Sun Photographs depict significant events in Las Vegas, Nevada from 1948 to 1989 that were covered by the newspaper. The photographs partially document the gubernatorial, senatorial, mid-term, and local elections in Nevada in 1982. The photographs also include protests by African Americans for better wages and renters for fair housing practices, McCarran Airport, protests against the Nevada Test Site, the Las Vegas Strip and downtown Las Vegas, hotels and casinos, political events, parades, dedications of buildings, and aerial photographs of the city. The photographs also depict politicians during campaign events and fundraisers, including President Ronald Reagan; U.S. Senators Howard Cannon, Pat McCarran, Chic Hecht, Paul Laxalt, and Harry Reid; Nevada governors Mike O'Callaghan and Robert List; and Lieutenant Governor Bob Cashell.

The Harmon Family Photograph Collection contains black-and-white and color photographic prints, negatives, postcards, and slides of the Harmon family in Las Vegas and Boulder City, Nevada between approximately 1900 and 1983. Las Vegas photographs depict the Harmon family in their home, at a ranch, and at Las Vegas High School. Boulder City photographs include a wedding and a view of Black Canyon, Nevada. Lastly, the collection also includes photographs of the Harmon family with various people, including the Wengert family and Howard Cannon, at receptions, ceremonies, and posing in front of Las Vegas buildings.