The Yucca Mountain Environmental Safety Collection (1970-2011) consists of reports and impact studies collected by Clark County's Nuclear Waste Division library for documenting Yucca Mountain's potential health and safety risks to Southern Nevada. The reports contain documents pertaining to potential environmental, health, financial, and safety risks from the Yucca Mountain Nuclear Waste Repository, which is located in Nye County, Nevada. The collection contains scientific and social studies in support of and opposition to the site. The bulk of the collection includes licensing reports, site selection studies, and impact studies from transporting, storing, and handling radioactive waste and spent nuclear fuel.

The Benedict Family Papers materials date from roughly 1905-1998 and are comprised of correspondence and letters (1969-1971) written to Howard Hughes by the public. The collection also contains correspondence written to Robert Maheu, former chief executive of Nevada operations for Howard Hughes. The collection also includes a variety of casino and gambling related product catalogs, gaming guides for Las Vegas casinos, and of research papers and reports primarily relating to sports betting and cheating.

The Tobias Mattstedt Menu Collection (approximately 1990-2009) is comprised of menus documenting the restaurant industry in Las Vegas, Nevada, the United States, and internationally. The menus include restaurants located in Las Vegas casinos, most notably the MGM Grand, located in Las Vegas. Included in the MGM Grand menus are restaurants such as the Pearl, Tabu Ultra Lounge, and the Grand Wok and Sushi Bar. The collection also documents menus collected by Mattstedt that are not affiliated with the MGM Corporation. These include menus located in the United States, especially Hawaii, including menus from the restaurants Olio!, Nob Hill, Diego's, and Sea Blue. The collection also includes international menus with a focus on Asian countries. The material provides insight into menu design, food culture, and the Las Vegas service industry.

The Beckley Family Photograph Collection (approximately 1891-1982) consists of black-and-white photographic prints and negatives and color photographic slides. The images depict the Beckley family, their businesses in southern Nevada, and Las Vegas, Nevada as the city developed during the first half of the twentieth century. Also included are images of airplanes at the first Las Vegas airport Anderson Field, later renamed Rockwell Field in 1925, Fremont Street in Las Vegas, and postcards of mining towns across southern Nevada.

The University of Nevada, Las Vegas (UNLV) Office of the President Records is comprised of documents used in daily matters of the Office of the President from approximately 1950 to 2007. The records in the collection document the expansion of the UNLV campus, and the academic and athletics programs offered by the university.

The Southern Nevada Chapter of the American War Mothers Organization Records (1947-1995) are comprised primarily of scrapbooks containing correspondence and minutes, numerous newspaper clippings, and photographs. Also included are pamphlets on American War Mothers organizational rituals, bylaws, history, ceremonial ephemera, flags, and a Henderson Chapter Charter. The materials also contain items relating to the North Las Vegas Chapter, the Rose Garden Chapter, and the State Chapter.