The UNLV Libraries Single Item Accession Photograph Collection (approximately 1869-1999) contains photographs, postcards, negatives, and slides primarily pertaining to Southern Nevada, with a focus on Las Vegas, Nevada, collected by the University of Nevada, Las Vegas University Libraries, Special Collections and Archives. The collection primarily includes images of early Las Vegas, hotels and casinos along Fremont Street and the Strip, railroad infrastructure, local businesses, and residential neighborhoods. Also included are images of Hoover (Boulder) Dam's construction, MX Missile testing, Nevada mining camps, and the natural desert environment. Other images depict towns throughout Nevada including Boulder City, Henderson, Reno, Luning, Tonopah, Goodsprings, Delmar, Beatty, Panaca, Overton, Caliente, Logandale, and Aurora.

The Murphy-Farmer collection contains black-and-white photographic prints (approximately 1930-1959) depicting locations around southern Nevada, including Lake Mead, Hoover Dam, Las Vegas, and Boulder City, Nevada.

The Southern Nevada Educators Photograph Collection consists of reproduction black-and-white photographic prints and negatives that Donna Andress compiled. The majority of the images are portraits of educators in Southern Nevada, primarily educators who have schools in Clark County, Nevada named after them. Other portraits depict prominent Las Vegas citizens, including Leva and William Beckley.

The Nick Pratto Photograph Collection contains black-and-white photographic prints and negatives of Las Vegas, Nevada between approximately 1930 and 1950. The collection includes images of the 1940 and 1945 Helldorado parade, James Cashman Sr.'s Desert Love Buggy, and views of Gilmore Gas Station located at Fifth Street and Bonneville Avenue in 1934.

The Ray W. Baldwin Photograph Collection (approximately 1940 -1981) consists of black-and-white photographic prints, negatives, and slides. The images depict architect Ray W. Baldwin's structures in the Las Vegas, Nevada area, as well as other central and southern Nevada locations.

The Ernest Mitchell Pratt Photographs (approximately 1932-1936) consist of black-and-white photographic prints, signed and unsigned, taken by Pratt while Hoover Dam was under construction. Many prints are signed and mounted, and two are noted as award-winning photographs shown at the Annual International Salon of Camera Pictorialists in Los Angeles, California. There are additional working prints included alongside the final prints for most of the scenes. Also included in the collection is one small photograph of Pratt. This collection was formerly known as the Price Photograph Collection.

The UNLV Libraries Collection of Grace Nusser Photographs (approximately 1970-1980) contains black-and-white images from the Las Vegas Review-Journal depicting Boulder City, Nevada ranger Jack Weiler being interviewed after the arrest of Grace Nusser from 1937. Additional images include pictures used for Las Vegas Review-Journal article clippings pertaining to the crime and arrest. The photographs are reproductions of original images created between 1937 April 29 and 1937 May 24.