The Women's Organzations series (1969-2003) contains documents such as meeting minutes, fliers, notes, brochures, bylaws, event information, and general information that relate to Florence McClure's extensive involvement with women's groups that focused on political, health and social betterment efforts in Nevada. McClure often took a leadership or executive role in these organizations including the Soroptimists International of Greater Las Vegas and the American Association of University Women. McClure was also an active lobbyist for women's rights concerning sexual, domestic, and physical abuse. There are several folders that reflect this including: Community Action Against Rape; a copy of her scrapbook on the founding of CAAR; Community Coalition for Victim's Rights; Families of Murder Victims; Jean Nidetch Women's Center; National Association for Victim's Assistance; Nevada Network Against Domestic Violence; and Safenest.

The anti-nuclear and peace organizations and conferences series (1974-2005) is comprised of the Nevada Desert Experience's files on other related organization and their work. Materials include correspondence, informational brochures, newsletters, notes, national and international organizations, other and religious groups, and conference programs and notes.