The Albert S. Henderson Photograph Collection (1860s-1959) primarily contains black-and-white photographic prints of Albert S. Henderson and his family. Also included in the collection are photographic prints of Henderson during his tenure as a Nevada legislator and district judge. Other materials include postcards, negatives, and a tintype.

The George Kelly Ryan Photograph Collection (1929) depicts waterways in Southern Nevada and Northern Arizona. The collection consists of eight photographic prints and two photographic negatives depicting Saint Thomas, Black Canyon, Boulder Canyon, and the Colorado River.

The collection is comprised of various account and appointment books dating from approximately 1922 to 1972 kept by Las Vegas, Nevadan dentist, Dr. Jay Dayton "J. D." Smith, who operated a dental practice near 1st and Fremont streets. Also included in this collection are sympathy cards to Dr. Smith's family upon his passing, copies of his obituary from the Las Vegas Sun, copies of the Las Vegas Age with a front page article on Dr. Smith's appointment as U.S. Marshal, and a copy of the book K.O. Knudson: His Life by James Monroe Harvey.