The Lorelle Nelson Collection on Atomic Testing is comprised of newspaper clippings, magazine and journal articles, correspondence, press releases, fact sheets, fliers, informational handouts and booklets, and newsletters from approximately 1980 to 2009 concerning nuclear weapons testing at the Nevada Test Site, throughout the United States, and internationally. The collection includes information about anti-nuclear groups, committees, and associations, as well as information on the effects of radiation, nuclear fallout, lawsuits and court cases, events and protests, conferences, and local news coverage.

The Las Vegas, Nevada Gay, Lesbian, Bisexual, Transgender, and Queer/Questioning (LGBTQ) Collection documents the social and political activities of Las Vegas, Nevada's LGBTQ community from 1955 to 2020. The collection includes hundreds of newspaper articles about LGBTQ issues, ranging from AIDS to Nevada legislation. The collection also documents the presence of the LGBTQ community in Las Vegas, including material from gay bars, nightclubs, social clubs, advocacy and political organizations, entertainers, and student groups. Previously known as the Las Vegas Gay, Lesbian, Bisexual, and Transgender Collection.

The Dennis McBride Collection of Gay Erotica (1960-2006) contains a selection of pornographic publications, three VHS tapes of erotic films, and photographic prints mail ordered from gay erotica or physique photography studios. The three studios represented in this collection are Alexander Studio, Sierra Domino Studio, and Third World Studio.

The Nevada Official Bicentennial Book Collection (1975) contains materials related to the editing and publication of the book by the Nevada American Revolution Bicentennial Committee. It includes article submissions about Nevada history as well as a small amount of correspondence to Stanley Paher, the editor of the book.

The Inter-Tribal Council of Nevada Photograph Collection (approximately 1970-1979) consists of laminated black-and-white photographic reproductions that depict various Native American tribal groups in Nevada from the late 19th and early 20th centuries. The Northern Paiute, Southern Paiute, Shoshone, and Washoe tribes are represented in the collection. The images depict individuals attending Indian Day School, posing with items they crafted, and going about daily life. All items in this collection are reproductions provided by the Nevada Historical Society and the Inter-Tribal Council of Nevada.

The Nevada Nurses Association Photograph Collection (approximately 1980-1990) is comprised of seventy-six photographic slides, and six color photographic prints that depict the Nevada Nurses Association conference held at the Sahara Hotel and Casino in Las Vegas, Nevada. The collection also includes black-and-white negatives from the 1986 Legislators' brunch in Las Vegas, Nevada.

The Carolyn Merriam Collection on the Sands Hotel (1972-1998) consists primarily of Sands Hotel merchandise and ephemera, including mugs, glassware, playing cards, dice, an ashtray, and a tote bag. The collection also contains several framed photograph reproductions depicting Las Vegas, Nevada in the 1950s and 1960s. The Sands Hotel operated in Las Vegas, Nevada from 1952 to 1996.