The Maurine and Fred Wilson and Dr. William S. Park Photograph Albums (1900-1930s) consist of twelve albums containing black-and-white photographic prints and three black-and-white photographic negatives. The photographs are primarily related to the families of William S. Park, John S. Park, and Fred and Maurine Hubbard Wilson. Included are images of the Park homes in Las Vegas, Nevada; Park and Wilson family members; scenes of early Las Vegas, Nevada; outdoor activities, and vacation trips to California, Colorado, and Mexico.

The Howard Hughes Professional and Aeronautical Photographs contain black-and-white photographs of businessman and entrepreneur Howard Hughes and his companies from 1916 to 1997. The photographs primarily depict Hughes alongside his aircraft, including the XF-11 prototype reconnaissance plane and the HK-1 Hercules, better known as the "Spruce Goose" or "Flying Boat." The photographs also cover the companies owned by Hughes, including Hughes Tool Company, Hughes Aircraft Company, Hughes Electronics Corporation, and RKO Pictures.

The Richard Ronzone Photographs depict Las Vegas, Nevada storeowner and politician Richard “Dick” Ronzone and his family from 1920 to 1989 and 2001. The photographs primarily depict Ronzone at Ronzone’s Store in Las Vegas, at events with politicians such as Nevada Governor Paul Laxalt, or at the Las Vegas Valley Water District. The photographs also depict Ronzone during his service with the Nevada National Guard; portraits of Ronzone, his wife Ann Roeth Ronzone, and his mother Bertha Ronzone; and events during Ronzone’s tenure as a Clark County Commissioner from 1972 to 1980.

The University of Nevada, Las Vegas School of Nursing Records (1950-2019) contain records documenting the history of the UNLV School of Nursing. The materials include records from the nursing school's Alumni Association, including financial reports, bylaws, correspondence, and membership information; recruitment materials from the School of Nursing, including brochures, photographs, and program requirements; history of the School of Nursing, including photographs, newspaper clippings, a short summary of the program, and a short documentary film comprised of digital video files; and accreditation information, including newspaper articles, accreditation reports, and evaluations of the program from the Nevada State Board. The materials also include nursing student uniforms, caps, and nursing capes from the 1950s and 1960s.

The Shar Rednour and Jackie Strano Papers on S.I.R. Productions (1981-2015) contain the personal and professional papers of Rednour and Strano, two lesbian filmmakers, writers, and activists from the 1990s until the 2010s. The collection contains the personal papers of both Rednour and Strano, including correspondence between the pair before they married in 2006. The collection also contains the professional files of Rednour and Strano in their capacity as creators of SIR (Sex, Indulgence, and Rock and Roll) Video in 1998. Materials include financial documents, correspondence, scripts and editing notes, crew information, publicity photographs, and direct order forms for S.I.R. Productions. In addition to records on SIR Video, the collection also contains a number of sex-positive and lesbian, gay, bisexual, transgender, and queer (LGBTQ) publications from the LGBTQ scene in San Francisco, California during the 1990s.

The University of Nevada, Las Vegas Solar Decathlon Records (2013-2021) are comprised of records documenting the University of Nevada, Las Vegas's participation in the U.S. Department of Energy (DOE) Solar Decathlon collegiate competition. The collection includes records created by the 2013, 2017, and 2020 UNLV teams (Team Las Vegas) in designing and building their respective competition entries: DesertSol, Sinatra Living, and Mojave Bloom. Records include competition application files, working project files, As-Built submittal packets, and promotional and marketing files for the competition. The majority of records in this collection represent the 2017 competition. Archived websites and social media accounts associated with Team Las Vegas and the Solar Decathlon competition are also included in the collection. The records document Team Las Vegas's efforts in designing and building energy efficient homes for the Solar Decathlon competition.

The Amy Ayoub Papers (1906-2022) document the life and career of Amy Ayoub, a long-time resident of Las Vegas, Nevada. The collection consists of correspondence, photographs, newspaper clippings, research, and other material that document the numerous facets of Ayoub's life. The collection covers many areas: Ayoub's early childhood; her family, including father Bobby Ayoub and stepfather Raymond Sutton; her financial consulting career and political work; her experience working as a prostitute in Nevada and subsequent documentary about being sex trafficked and working in brothels; time spent as the first female Nevada Athletic Commissioner; and more. Digital files include audio and video files of Mike Tyson's 2002 licensure hearing, and video of Ayoub's testimony before the Nevada State Assembly Judiciary Committee for Assembly Bill 67 in 2013. There are also digitized photographs that Ayoub used for the documentary The Zen Speaker: Breaking the Silence.