The collection is comprised of architectural drawings (1952-1997) completed by American architect, Ethan Jennings Jr. and/or his architectural firm, Ethan Jennings Jr., AIA, CSI and includes Jenning's work from the firm of John Badgley, AIA, where Ethan Jennings Jr. worked in Southern California during the 1950s, as well as work Jenning's completed with Americo Inc., and Tolosa Group. The collection contains 217 sets of drawings, 6 boxes of project records, and 8 flat files of oversized material from over 200 different projects primarily located in California with some projects located in the Las Vegas area. The materials feature hand-drawn architectural drawings, ranging from preliminary sketches to construction documents. The drawings also contain work from consultants, engineers, and other architects who collaborated on the development of the various projects. The drawings include: commercial, industrial, professional, civic, residential, and religious buildings of varying scales, such as libraries, apartments, warehouses, office developments, schools, military buildings, churches, and custom single-family homes located throughout California and Las Vegas. The drawings also include a number of additions, remodels, and renovations. The collection also contains project records like structural calculations and drawings, project manuals and specifications, bid documents, and professional correspondence.

The Benedict Family Papers materials date from roughly 1905-1998 and are comprised of correspondence and letters (1969-1971) written to Howard Hughes by the public. The collection also contains correspondence written to Robert Maheu, former chief executive of Nevada operations for Howard Hughes. The collection also includes a variety of casino and gambling related product catalogs, gaming guides for Las Vegas casinos, and of research papers and reports primarily relating to sports betting and cheating.

The Domingo Cambeiro Corporation Architectural Records contain renderings and presentation boards depicting schools, commercial properties, public facilities, and government buildings throughout Las Vegas, Nevada between 1979 to 2010. The collection also includes architectural drawings of the Thomas & Mack Center on the campus of the University of Nevada, Las Vegas.

The Richard "Dick" Stabile Music Scores (1899-1986) is comprised primarily of musical scores arranged, composed, and performed by big-band leader and musician Dick Stabile. The scores, dating between 1941 and 1980, include popular music arrangements and original compositions, including original orchestra music for the documentary film Born to Buck. Also included in the collection are commercially produced popular music sheets published between 1899 and 1986.

The McCall Family Papers are comprised primarily of family photographs and correspondence from 1910-1970. The materials concentrate on Quannah McCall and his daughter, Connie McCall, both were well known dentists in Southern Nevada. The materials also contain letters, postcards, holiday cards, and birth, death, and marriage certificates, as well as school commencement announcements for family members.

The Sister Klaryta Antoszewska Photograph Collection (1977-1991) consists of photographic slides that depict various Nevada, United States, and international nuclear test protests. The collection includes images of Sister Klaryta Antoszewska and Sister Rosemary Lynch, as well as images of the Lenten Desert Experience and numerous protests at the Nevada Test Site. Also included are images of nuclear testing, soldiers, and anti-nuclear testing promotional materials.

The Beckley Family Photograph Collection (approximately 1891-1982) consists of black-and-white photographic prints and negatives and color photographic slides. The images depict the Beckley family, their businesses in southern Nevada, and Las Vegas, Nevada as the city developed during the first half of the twentieth century. Also included are images of airplanes at the first Las Vegas airport Anderson Field, later renamed Rockwell Field in 1925, Fremont Street in Las Vegas, and postcards of mining towns across southern Nevada.