The Young Electric Sign Company (YESCO) Corporate Records (1914-2000) document the history of the Young Electric Sign Company (YESCO) and is comprised of photographs of sign production and finished signs, negatives, slides, transparencies, anniversary scrapbooks, and videotapes. The collection also contains meeting minutes, correspondence, price books, drawings, calculations, newspaper and trade magazine articles on YESCO, advertising materials, and oral history interviews and audio recordings of YESCO designers and executives. YESCO is responsible for many of the neon signs in and around Las Vegas, Nevada and Reno, Nevada, as well as other Western states.

The Thomas Hickey Political Papers (1964-1996) contain the professional files of Hickey’s career as a Nevada State Assemblyman and Senator. Materials include constituent correspondence, voting records, memoranda, newspaper clippings, bills, and research documentation on topics such as the Yucca Mountain Nuclear Waste Repository, the Equal Rights Amendment (ERA), education, health, prisons, finance, and Nevada infrastructure. The collection highlights Hickey’s role on committees including finance, transportation, government affairs, and ways and means.

The Howard Hughes Professional and Aeronautical Photographs contain black-and-white photographs of businessman and entrepreneur Howard Hughes and his companies from 1916 to 1997. The photographs primarily depict Hughes alongside his aircraft, including the XF-11 prototype reconnaissance plane and the HK-1 Hercules, better known as the "Spruce Goose" or "Flying Boat." The photographs also cover the companies owned by Hughes, including Hughes Tool Company, Hughes Aircraft Company, Hughes Electronics Corporation, and RKO Pictures.

The Robert Woodruff Photograph Collection (1900s-1970s) consists of ninety-seven black-and-white photographs of locations and events in Clark County, Nevada. Locations include Las Vegas, Henderson, and Searchlight, Nevada, as well as the Hoover Dam. The majority of the images were taken between 1934 and 1962.

The University of Nevada, Las Vegas Solar Decathlon Records (2013-2021) are comprised of records documenting the University of Nevada, Las Vegas's participation in the U.S. Department of Energy (DOE) Solar Decathlon collegiate competition. The collection includes records created by the 2013, 2017, and 2020 UNLV teams (Team Las Vegas) in designing and building their respective competition entries: DesertSol, Sinatra Living, and Mojave Bloom. Records include competition application files, working project files, As-Built submittal packets, and promotional and marketing files for the competition. The majority of records in this collection represent the 2017 competition. Archived websites and social media accounts associated with Team Las Vegas and the Solar Decathlon competition are also included in the collection. The records document Team Las Vegas's efforts in designing and building energy efficient homes for the Solar Decathlon competition.

The Mike O'Callaghan Professional Papers (1943, 1968-2004) mainly consist of research files gathered by Mike O'Callaghan in his post-political capacity as executive editor of the Las Vegas Sun as well as owner and publisher of the Henderson Home News, Boulder City News, and Green Valley News. The papers also contain handwritten and typewritten drafts of O'Callaghan's "Where I Stand" article for the Las Vegas Sun, along with his reporter's notebooks, monthly planners, and photographic prints. The research files cover a wide variety of topics, including but not limited to environmental issues; nuclear waste; state and local politics; military and veterans affairs; foreign relations including Israel, Iraq, and Korea; and education. The collection also contains copies of speeches given by O'Callaghan as the 23rd Governor of Nevada between 1971 and 1979, some of which contain handwritten notations.

The Bob Coffin Political Papers (approximately 1861-2021) document the political career of independent Democrat Bob Coffin who served in the Nevada Assembly, State Senate, and Las Vegas City Council from 1983 to 2019. Collection materials primarily consist of legislative research files associated with Coffin's committee assignments. City Council records in this collection include budget files, constituent concerns, and city project files. The collection also includes election materials used for Coffin's political campaigns and include posters, mailers, as well as newspaper clippings and information on Coffin's opponents.