The University of Nevada, Las Vegas Photograph Collection (approximately 1900-2004) depicts the development of the university and the city of Las Vegas. The collection includes images of campus buildings, student activities, sports teams, past university presidents, and Las Vegas in the early twentieth century. Early images depicting the surrounding area are included in this collection as well.

The Jacob E. Von Tobel Photograph Collection contains black-and-white photographs of the pioneer Von Tobel family from 1900 to 1980. The collection includes photographs of the Von Tobel family, early Las Vegas, Nevada buildings and landmarks, and aerial photographs of Las Vegas and surrounding areas.

The James Cashman Sr. Photograph Collection (approximately 1905 to 1975) consists of black-and-white photographic prints, negatives, slides, and albums as well as a glass plate negative. The photographs depict four major subjects: Cashman's family, friends, and associates; Cashman's businesses; the Hoover Dam and Colorado River; and various locations across Nevada.

The George Laurence Ullom Photograph Collection (1915-1974) contains photographic prints and negatives created by Las Vegas, Nevada photographer George Laurence "Larry" Ullom. Larry owned and operated Ullom’s Desert Art Studio, which was located in Las Vegas, Nevada. The bulk of the collection consists of Ullom's wedding chapel photography. The collection also includes his photography work for the Bureau of Reclamation, the Agricultural Extension Service, and the Associated Press, Atlantic News, and Acme news bureaus.

The Lori Lipman Brown Papers date from 1975 to 2009 and document former Nevada State Senator Lori Lipman Brown's political career. It includes correspondence and materials from Brown's service as a Nevada State Senator from 1992 to 1994, case files from her defamation lawsuit against Nevada State Senator Kathy Augustine, and papers from her work opposing the Nevada Question 2 ballot measure on same-sex marriage in 2000. The collection also contains photocopies of biographical materials and personal and publicity photographs of Brown, as well as material from her time working with local high school and commmunity theatre programs.

The Florence McClure Papers (1969-2007) are comprised of writings, correspondence, newspaper clippings, handwritten notes, and assorted publications that focus on McClure's work with women's organizations, her efforts on behalf of the Southern Nevada Women's Correctional Facility, and her political advocacy work. It also contains a large number of reference clippings McClure collected on women's issues from local, national, and international publications.