The Las Vegas, Nevada Gay, Lesbian, Bisexual, Transgender, and Queer/Questioning (LGBTQ) Collection documents the social and political activities of Las Vegas, Nevada's LGBTQ community from 1955 to 2020. The collection includes hundreds of newspaper articles about LGBTQ issues, ranging from AIDS to Nevada legislation. The collection also documents the presence of the LGBTQ community in Las Vegas, including material from gay bars, nightclubs, social clubs, advocacy and political organizations, entertainers, and student groups. Previously known as the Las Vegas Gay, Lesbian, Bisexual, and Transgender Collection.

The Ted Lenhart LGBTQ Community Collection (1990-2001) is comprised of correspondence, newspaper clippings, and organizational material detailing LGBTQ community issues in Nevada throughout the 1990s. The collection includes materials from organizations including: Aid for AIDS of Nevada, the Clark County Coalition of HIV/AIDS Service Providers, the Nevada chapter of the AIDS Coalition to Unleash Power (ACT-UP), efforts to organize an HIV-Negative Men’s support group in Nevada, and Nevada Outdoors, an LGBTQ hiking club.

The Las Vegas LGBTQ Community Center of Southern Nevada Audiovisual Collection contains seventeen VHS tapes which contain recordings of "Beyond the Rainbow" a Gay and Lesbian Center of Southern Nevada Cable show; the LGBTQ Center of Southern Nevada 1998 and 1999 Honorariums; and news program relating to "Pride Ride 2000." "Beyond the Rainbow" was a weekly cable show sponsored by the Gay and Lesbian Community Center of Southern Nevada created not just to reach the LGBTQ+ community, but anyone interested in learning more about the community and the issues faced by its members. Programming explored a number of topics including employment, personal safety, families, relationships, diversity, and spirituality.