The Howard Hughes Professional and Aeronautical Photographs contain black-and-white photographs of businessman and entrepreneur Howard Hughes and his companies from 1916 to 1997. The photographs primarily depict Hughes alongside his aircraft, including the XF-11 prototype reconnaissance plane and the HK-1 Hercules, better known as the "Spruce Goose" or "Flying Boat." The photographs also cover the companies owned by Hughes, including Hughes Tool Company, Hughes Aircraft Company, Hughes Electronics Corporation, and RKO Pictures.

The Hughes Electronics Corporation Records (1935-2021) contain the files and publications of the corporate communications department and records donated by Robert K. Roney, a leading engineer at Hughes. These records document the growth of the company in Southern California, from building experimental aircraft for Howard Hughes, to developing and manufacturing radar and guided missile systems for the United States military and NATO forces, to developing and manufacturing communication satellites and space probes for NASA, and becoming the largest manufacturer of communication satellites and provider of satellite TV. The collection contains press releases, executive biographies, executive speeches, annual reports, corporate directories, organizational charts, correspondence files, technical reports and notes, promotional materials, as well as articles and publications detailing the history of the company. The collection also includes audiovisual materials and photographs. The audiovisual series details the history of the company through news footage and documentaries about Howard Hughes, aviation, corporate mergers, interviews with executives and promotional videos.

The Howard Hughes Film Production Records (1912-1992) represent Howard R. Hughes, Jr.'s Hollywood film production achievements through records from companies owned or established by Hughes. The bulk of the records date between 1926 and 1960 and include production and corporate materials from sixteen films, as well as materials related to Hughes' organizations outside of film development. Materials include documents, photographic prints and negatives, blueprints, line drawings, newspaper clippings, posters, paintings, and artifacts.