The Lake-Eglington Family Photograph Collection contains photographs of the Lake-Eglington Family in and around Las Vegas, Nevada from 1900 to 1976. The materials include photographs of early Las Vegas resident Olive Lake-Eglington and her family shortly after they moved to Las Vegas in 1904, as well as her eventual husband Earle Eglington after he moved to Las Vegas in 1911. The materials also include photographs of Native American artifacts, schools in Clark County, Nevada, artesian wells, the Hoover (Boulder) Dam, the Colorado River, Mt. Charleston, the Mormon Fort, the Stewart (Kiel) Ranch, the Las Vegas Ranch, and many early residents of Las Vegas.

The Jay Sarno Photograph Collection (1947-1983) contains photographs from hotel and casino developer Jay Sarno. The photographs primarily depict Sarno and his family. The photographs also depict some of Sarno's development projects, including Circus Circus, Caesars Palace, and the Grandissimo. The photographs depict construction of the hotels, events, and famous figures.

The Scott Henry Photographs of the Las Vegas, Latinx Community (approximately 1983-2000) consist of 42 photographic prints depicting members of the Latinx community in Las Vegas, Nevada. Thirty-eight of the prints were used as part of a collaborative project between Scott Henry, photographer and editor for the Las Vegas Review-Journal, and Thomas Rodriguez, a prominent member of the Latinx community in Las Vegas, for an exhibit of the Las Vegas Latinx community. Henry and Rodriguez together planned who to photograph for the exhibit. The photographs demonstrate the impact that the Latinx community has on the region's political, economic, and social growth and development. A number of the photographs show early members of the League of United Latin American Citizens (LULAC), including John Mendoza, Delia Martinez, Tom Rodriguez, Bob Agonia, Corrine Gutierrez, Nick Flores, Grace Salazar, and Gus Ramos.

The Donna Andress Papers (1890-2021) contain the personal papers of Donna Andress, a longtime resident and activist in Southern Nevada. Materials include correspondence and newspaper clippings from the Nevada Welfare Committee, on which Andress served as chairperson during the 1970s, in addition to pamphlets and newsletters from various Nevada historical organizations and committees. The papers reflect her involvement with community organizations throughout Southern Nevada.

The Clyde F. Merrick Photographic Slides (approximately 1971-1979) contain color photographic slides taken by Clyde F. Merrick, longtime resident of Las Vegas, Nevada. The majority of slides in this collection depict signs for different businesses around Las Vegas including the Las Vegas Strip and the Westside. Some of the businesses documented in this collection includes Fong's Garden, Leon's Shear Magic Beauty Salon, Lucas and Son's Antiques, Dick's Tricky Trikes, Mohan's Custom Tailors, the Twenty Grand Club, Owens TV Repair, and Caesars Palace. The collection also documents a variety of different types of businesses around Las Vegas including bars and nightclubs, beauty salons, car washes, gas stations, and restaurants. Merrick was also a car racing hobbyist and a number of slides in this collection depict what is presumed to be the Las Vegas Speedrome racetrack (later known the Las Vegas Motor Speedway). This collection also includes photographs of locations outside of Las Vegas and Southern Nevada.

The William Flangas Srapbooks document his anti-smoking efforts in Nevada from 1974 to 2014. These materials include correspondence, articles, copies of assembly bills, newsletters related to smoking and health, and newsletters related to non-smokers.

The Felix Lenox Photograph Collection (approximately 1910-2000) contains original photographic slides, prints, and contact sheets collected by Lenox in support of his popular "Nevada Armored Transport Inc. (1946-1984)" Facebook page. The collection also includes Lenox's own research on Las Vegas history and armored trucks.