The McCall Family Papers are comprised primarily of family photographs and correspondence from 1910-1970. The materials concentrate on Quannah McCall and his daughter, Connie McCall, both were well known dentists in Southern Nevada. The materials also contain letters, postcards, holiday cards, and birth, death, and marriage certificates, as well as school commencement announcements for family members.

The Yucca Mountain Environmental Safety Collection (1970-2011) consists of reports and impact studies collected by Clark County's Nuclear Waste Division library for documenting Yucca Mountain's potential health and safety risks to Southern Nevada. The reports contain documents pertaining to potential environmental, health, financial, and safety risks from the Yucca Mountain Nuclear Waste Repository, which is located in Nye County, Nevada. The collection contains scientific and social studies in support of and opposition to the site. The bulk of the collection includes licensing reports, site selection studies, and impact studies from transporting, storing, and handling radioactive waste and spent nuclear fuel.

The Chester Longwell Photograph Collection consists of 608 black-and-white photographic prints dating from approximately 1910 to 1930. The images primarily depict the Longwell family's excursions in the Southern Nevada region, primarily to Mount Charleston, Nevada. Also included are images of Southern Nevada mines and mining towns, as well as Pubelo Grande de Nevada, the Lost City. The remaining images depict geological formations and features, as well as forestry and nature scenes in Nevada and Arizona.

The Ferron and Bracken Photograph Collection depicts Southern and Central Nevada and other western states from 1890 to 1961. The photographs primarily depict the development and growth of early Las Vegas, Nevada; mines and mining operations in Southern and Central Nevada; towns and mines in Nevada; and the Hoover (Boulder) Dam and the Colorado River.

Oral history interview with Stella Champo Iaconis conducted by Kay Long on May 14, 1997, May 21, 1997, May 26, 1997, and September 22, 1997 for the Women's Research Institute of Nevada (WRIN) Las Vegas Women Oral History Project. Iaconis opens her interviews discussing her difficult upbringing and life on a ranch in Las Vegas, Nevada with her dad in the 1910s and 1920s. Iaconis then describes her experiences as a waitress in Las Vegas. As the interviews continue, Iaconis discusses Block 16 and sex work, the Helldorado Days, and life in 1930s Las Vegas. Iaconis ends the interview talking about her father and his career as a miner; her many husbands; and her personal history in Las Vegas.

The Harrah’s Entertainment, Inc. Photograph Collection contains black-and-white and color photographic prints, negatives, postcards, and slides of William "Bill" Harrah at events in Nevada between approximately 1930 and 1991. Also included are views of Harrah’s Nevada properties including Harrah’s Lake Tahoe Hotel and Casino, Harrah’s Reno Hotel and Casino, and the Holiday Inn Hotel and Casino (that later became Harrah’s Las Vegas Hotel and Casino).

The Sister Klaryta Antoszewska Photograph Collection (1977-1991) consists of photographic slides that depict various Nevada, United States, and international nuclear test protests. The collection includes images of Sister Klaryta Antoszewska and Sister Rosemary Lynch, as well as images of the Lenten Desert Experience and numerous protests at the Nevada Test Site. Also included are images of nuclear testing, soldiers, and anti-nuclear testing promotional materials.