The Alpha Kappa Alpha Sorority, Incorporated, Theta Theta Omega (AKA TTO) Chapter records (1965-2020) are comprised of organizational records, conference programs, digitized copies of the chapter's scrapbooks, and copies of Ivy Leaf, the organization’s national newsletter. The records include chapter and committee agendas and meeting minutes, Far Western Regional Conference reports, and fliers for events hosted by AKA TTO. Also included are archived web captures of AKA TTO's website and digital audio and video files for the chapter's oral history project interviewing Charter, Golden, and Silver members from 2019 to 2020.

The Ferron and Bracken Photograph Collection depicts Southern and Central Nevada and other western states from 1890 to 1961. The photographs primarily depict the development and growth of early Las Vegas, Nevada; mines and mining operations in Southern and Central Nevada; towns and mines in Nevada; and the Hoover (Boulder) Dam and the Colorado River.

The Archie C. Grant Photograph Collection (1914-1968) contains black-and-white photographs of Nevada politician Archie C. Grant. The materials include photographs of Grant with the Las Vegas Housing Authority at groundbreaking ceremonies, the University of Nevada Board of Regents, and with other Nevada politicians. Materials also contain early photographs of the University of Nevada, Las Vegas campus, including the dedication of Maude Frazier Hall.

The Gay and Lesbian Community Center of Southern Nevada Photograph Collection contains mainly candid photographs of events and individuals affiliated with the Las Vegas-based Gay and Lesbian Community Center of Southern Nevada (GLCCSN) dating from 1993 to 2000. Photographs depict events honoring prominent members of the gay, lesbian, bisexual, transgender, and queer community; meetings at GLCCSN; and candidate nights for members of the community running for public office. The collection also includes a number of photographs of the Freedom to Marry celebration at the GLCCSN and the Gay Pride Las Vegas festival from 1998 to 1999.

The University of Nevada, Las Vegas (UNLV) Office of the President Records is comprised of documents used in daily matters of the Office of the President from approximately 1950 to 2007. The records in the collection document the expansion of the UNLV campus, and the academic and athletics programs offered by the university.

The Yucca Mountain Environmental Safety Collection (1970-2011) consists of reports and impact studies collected by Clark County's Nuclear Waste Division library for documenting Yucca Mountain's potential health and safety risks to Southern Nevada. The reports contain documents pertaining to potential environmental, health, financial, and safety risks from the Yucca Mountain Nuclear Waste Repository, which is located in Nye County, Nevada. The collection contains scientific and social studies in support of and opposition to the site. The bulk of the collection includes licensing reports, site selection studies, and impact studies from transporting, storing, and handling radioactive waste and spent nuclear fuel.