The collection includes materials from the Nevada Test Site (1955-1967) including newsletters published by the Reynolds Electrical & Engineering Co., Inc. and photographs of Southern Nevada flora, fauna, and archaeology. It also includes photographs of test explosions at the Nevada Test Site, as well as photographs documenting a visit from North Atlantic Treaty Organization (NATO) officials and a visit from John F. Kennedy to the Nevada Test Site. The collection also contains an oversized poster of an atomic explosion and one of a nuclear rocket development station.

The Thomas P. O'Farrell Papers (1900-1999) are comprised of scientific reports collected by Thomas O’Farrell over the course of his career studying wildlife ecology, particularly its connection to nuclear radiation. Materials include original, reprinted, and photocopied editions of scientific reports on animal and plant life around the world, focusing primarily on the Mojave and Great Basin Deserts, Alaska, Washington, and the Pacific Ocean. Reports come from institutions including the Desert Research Institute (DRI), Oak Ridge National Laboratory (ORNL), the Environmental Protection Agency (EPA), the Energy Research and Development Administration (ERDA), and the United States Department of Energy (DOE), as well as affiliated universities.

The George Knox Roth Collection (1959-1980) consists of newspaper clippings (including photocopies), magazine articles, newsletters, technical reports and publications, correspondence, notes, and photographs relating to the Atomic Energy Commission, the environmental impact of nuclear testing in Nevada, Nevada mining, Airwest and the Hughes Airport, and other aspects of Howard Hughes’ Nevada operations. The George Knox Roth Collection also includes correspondence and expense reports related to his own company, General Research Consultants.

The Sierra Club Toiyabe Chapter Records (1951 to 2021) are composed of files from Sierra Club officers and environmental activists in the Southern Nevada (formerly Las Vegas) Group of the Toiyabe Chapter. The collection documents the involvement of the Southern Nevada group in a variety of environmental concerns, such as air quality, transportation, urbanization, and nuclear issues, in which the chapter has expressed interest. The records are comprised of correspondence, memoranda, meeting minutes and agendas, newspapers, magazines, newsletters, pamphlets, press releases, legislation, recommendations, resolutions, and general information. Due to the group’s location in the heart of the Mojave Desert, the collection provides excellent case studies of significant changes in the post-World War II American environmental movement, notably the increased recognition of the worth of desert lands.

The Greenpeace Pacific Southwest Records are comprised of files and documents pertaining to environmental activism in Southern Nevada from 1962 to 1994, primarily addressing the organization of protests at the Nevada Test Site. The collection contains newspaper articles, newsletters, publications, financial records, protest information, correspondence, meeting minutes, articles of incorporation, Freedom of Information Act requests, and Nevada Test Site information. Also contained in the collection are maps and documents related to various environmental issues such as nuclear waste, land use, wildlife protection, and international environmental activism.