The collection is comprised of drawings (1965-1996) completed by American architect Gary Guy Wilson and/or his architectural firm, Gary Guy Wilson, AIA, Architect Studios and contains 613 sets of drawings from over 250 different projects. Primarily focused on the Las Vegas, Nevada area, the materials feature hand-drawn architectural drawings, ranging from preliminary sketches to construction documents, and a number of printed computer aided drawings. The drawings also contain work from a number of consultants, engineers, and other architects who collaborated on the development of the various projects. The drawings include: commercial and professional buildings of varying scales, such as convenience stores, hotels, casinos, shopping centers, and office developments; schools; military buildings at both Nellis and Indian Springs Air Force Bases; multi-family residential developments; and custom single-family homes located throughout the Southwest (United States).

The Ralph Denton Legal Papers (1950-1993) consist of case files and legal briefs of civil rights attorney Ralph Denton. The cases largely involve civil rights issues and property claims in Las Vegas, Nevada. The files include cases representing individuals as well as companies such as Henderson Telephone Company, Lephrechaun Mining Company, and the Jockey Club Casino.

The Joseph "Wingy" Manone Papers (1934-1996) include a partial draft of his autobiography, newspaper clippings, correspondence, magazine articles, and press releases related to his musical career. Manone also wrote music, some of which is included in the collection.

The Soroptimist International of Greater Las Vegas and Paradise Valley Records document the activity of two Las Vegas, Nevada chapters of the women's advocacy group Soroptimist International from 1968 to 2000. The records contain membership information, by-laws, correspondence, scrapbooks, publications, memoranda, and ephemera about women's issues, environmental concerns, and the club's activities in the Greater Las Vegas and Paradise Valley chapters. The records also contain information from conferences held by Soroptimist International, including audio cassette recordings of speeches and presentations.

The Cork Proctor Papers document the career of comedian Cork Proctor from 1942 to 2012. The papers include photographs, programs, advertisements, and newspaper articles that illustrate both the longevity and influence of one of Nevada's most famous comedians. From 1972 to 2012, in both Reno and Las Vegas, Proctor consistently worked as a stand-up comedian, writer, and roaster.

The Rick L. May Papers document social and political activities of Las Vegas, Nevada's lesbian, gay, bisexual, and transgender (LGBT) community from 1982 to 1997. The papers include records from the Gay Academic Union of the University of Nevada, Las Vegas; various gay pride celebrations in Los Angeles, California and Las Vegas; the Metropolitan Community Church's outreach to the LGBT community; as well as Rick L. May's own notes and collections about LGBT-supportive stores like R and R Assordid Sundries. The collection also includes several t-shirts that commemorate the pride celebrations. The papers demonstrate how the pride celebrations that began in 1984 were the result of efforts from several sectors of Las Vegas' LGBT community.

The Frederickson Family Papers (1904-1917) contain documents and photographs related to Goodsprings, Nevada settlers John C. and Elizabeth Frederickson. Materials include bank statements, mining statements, personal correspondence, and college notes.