The MGM Grand Hotel Fire Photographs (1980) is comprised of twenty-eight photographic prints of the MGM Grand Hotel fire, which occurred on November 21, 1980. Photographs show the hotel-casino on fire as well as the resulting damages to the property. The photographs were taken by the Tracinda Corporation which was MGM Grand Hotel owner Kirk Kerkorian's investment holding company.

The Bob Paluzzi Panoramic Photographs (1978-2005) contain the work of photographer Robert "Bob" Paluzzi. Paluzzi began documenting local events and locations in Las Vegas, Nevada during the mid-1970s and continued photographing locations across the United States and internationally until 2005. The collection contains original photographic negatives (black-and-white and color) and photographic prints that depict sporting events and places throughout Las Vegas and the surrounding region. Additional locations include cities across the United States, and international locations including Paris, France; Brussels, Belgium; and London, England. A number of the images are from major sporting events that took place outside Las Vegas, such as Super Bowls XIV to XXXIX and Major League Baseball World Series games.

The Eric A. Jamieson Photographs contain photographic slides of the Western United States' Intermountain region from 1955 to 1983. The bulk of the images are of the region's physical and urban landscapes and include Las Vegas, Nevada, the Las Vegas Strip and Fremont Street, Nevada mining towns, Red Rock Canyon, Mount Charleston, Valley of Fire, Lake Mead, and Death Valley.

The Francisco Arcaute Photographs (2004-2006) contain monochrome and color photographic negatives of various exterior environs, signage, and events around Las Vegas, Nevada and Southern Nevada taken by Chicago, Illinois-based photographer Francisco Arcaute. The materials include negatives of neon signs located at the Fremont Street Experience, the El Cortez Hotel and Casino, and the Blue Angel Motel. Events represented in this collection include the annual Veterans Day parade hosted by the Veterans Action Group and Christmas markets.

The Bill Hughes Photographs (approximately 1980-2012) contains negatives, slides, prints, proofs, and born digital images created by local photographer and photojournalist Bill Hughes for publications including Las Vegas CityLife, Las Vegas Business Press, Las Vegas Weekly, as well as commercial clients. A portion of prints in the collection consist of modeling photographs Hughes took as part of his business. The digital images represent a variety of clients, and feature local bands, DJs, and performers in nightclubs and bars on the Strip and downtown Las Vegas. Also included in digital files are portraits, artistic photographs and self-portraits, and material used for Las Vegas Weekly, CityLife, and Business Press.

The Claes Oldenburg Photograph consists of a single black-and-white photograph taken by Patricia Mortati in March 1981 of sculptor Claes Oldenburg. The photograph depicts Oldenburg watching the installation of the Flashlight, which is reflected in a window behind Oldenburg. The Flashlight is steel sculpture created by Oldenburg and artist Coosje Van Bruggen for the University of Nevada, Las Vegas's campus.

The Ferron and Bracken Photograph Collection depicts Southern and Central Nevada and other western states from 1890 to 1961. The photographs primarily depict the development and growth of early Las Vegas, Nevada; mines and mining operations in Southern and Central Nevada; towns and mines in Nevada; and the Hoover (Boulder) Dam and the Colorado River.