The Fred and Maurine Wilson Photograph Collection depicts the Wilson Family, events, and locations in Las Vegas, Nevada and the Southwestern United States from approximately 1860 to 1990. The photographs primarily depict early Las Vegas, including the Mormon Fort and Kiel Ranch; mines, towns, and railroads in Southern Nevada; the construction and planning of the Hoover (Boulder) Dam on the Colorado River; and the Wilson Family. The photographs also include prominent Las Vegas families such as the Park Family, aerial photographs of the city, landmarks on Fremont Street and downtown Las Vegas, and desert landscapes.

The Archie C. Grant Photograph Collection (1914-1968) contains black-and-white photographs of Nevada politician Archie C. Grant. The materials include photographs of Grant with the Las Vegas Housing Authority at groundbreaking ceremonies, the University of Nevada Board of Regents, and with other Nevada politicians. Materials also contain early photographs of the University of Nevada, Las Vegas campus, including the dedication of Maude Frazier Hall.

The Glenn Davis Photograph Collection (approximately 1914-1960) depicts life in Southern Nevada and the American Southwest. The images were created or collected by Las Vegas photographer Glenn Davis and include images of the construction on the Hoover Dam (formerly known as the Boulder Dam), landscapes, gaming, and residents of the region.

The Mary Griffith Toleno Photograph Collection contains photographs of Nevada from approximately 1875 to 1964. The materials include photographs of Fort Churchill, the Virginia and Truckee Railroad, the New York Mine in Silver City, Virginia City, buildings in Lovelock, Nevada, and locations in Carson City, Nevada and Reno, Nevada. The materials also include photographs of the Griffith family and friends.

The Tonopah-Goldfield Mining Photograph Collection depicts mining activities in the mining towns of Tonopah and Goldfield in Esmeralda County, Nevada from approximately 1901 to 1920. The photographs primarily depict mines, miners, mills, construction, ore, and workers transporting ore. The photographs also depict events and people in Tonopah and Goldfield, including parades, celebrations, banquets, children, Native Americans, and prominent buildings.

The James Berry Photograph Collection contains five black-and-white photographs of Nevada near Las Vegas from approximately 1930 to 1944. The materials include photographs of the Union Pacific Depot, Las Vegas High School, the Las Vegas Downs Racetrack, and the Army Air Force Base in Indian Springs, Nevada.

The Merle and Beulah Frehner Photograph Collection contains photographs of Southern Nevada from 1905 to 1955. The materials include photographs of the Frehner freight teams transporting ore, schools and students in the Moapa Valley, the Colorado River, and parades in Southern Nevada.