Dr. Darville Knowles was born in Miami, Florida, in 1948. His mother and father were schoolteachers in Dade County. After their divorce in 1962, Darville's mother relocated to Las Vegas with her two sons and took a teaching position here. Dr. Knowles comments on the differences between Miami and Las Vegas as far as segregation regarding housing, education, and job opportunities. He also mentions that his grandmother had emigrated from the Bahamas and that she impressed on them to make their own situation and community better. He recalls that track and field athletics were desegregated before the contact sports, such as football and basketball. Darville and his brother Michael (a lawyer in Miami) both graduated from college. Darville attended Howard University and Stanford University Medical School and completed his internship at the Jewish Hospital of St. Louis. Dan Wilkes, a family friend and pathologist in Las Vegas, convinced Darville to look at Las Vegas for job opportunities. After trying St. Louis, Atlanta, Houston, and Los Angeles, Dr. Knowles finally settled in Las Vegas in 1982 and "grew' his practice at Sunrise Hospital. Dr. Knowles comments on health problems in Las Vegas related to eating choices, lack of exercise, and poor air quality. He describes how HMOs have changed the practice of medicine and gives his opinions on how health care should be addressed by Congress. He also discusses the future of medicine, the research he was involved in, and the AIDS crisis. Dr. Knowles talks about how medicine has changed since 1982, the large number of respiratory problems that he treats, and comments further on HMOs and the fixture of medicine in Las Vegas. He also shares that he found time to author a murder mystery and has plans to write more.