The Las Vegas, Nevada Gay, Lesbian, Bisexual, Transgender, and Queer/Questioning (LGBTQ) Collection documents the social and political activities of Las Vegas, Nevada's LGBTQ community from 1955 to 2020. The collection includes hundreds of newspaper articles about LGBTQ issues, ranging from AIDS to Nevada legislation. The collection also documents the presence of the LGBTQ community in Las Vegas, including material from gay bars, nightclubs, social clubs, advocacy and political organizations, entertainers, and student groups. Previously known as the Las Vegas Gay, Lesbian, Bisexual, and Transgender Collection.

The Dottie Dee Dancers Photograph Collection (approximately 1940-2008) consists of black-and-white photographic reprints of the La Bard Dancers and the Dottie Dee Dancers at the El Rancho in Las Vegas, Nevada.

The Dennis McBride Collection of Gay Erotica (1960-2006) contains a selection of pornographic publications, three VHS tapes of erotic films, and photographic prints mail ordered from gay erotica or physique photography studios. The three studios represented in this collection are Alexander Studio, Sierra Domino Studio, and Third World Studio.

The Nevada Official Bicentennial Book Collection (1975) contains materials related to the editing and publication of the book by the Nevada American Revolution Bicentennial Committee. It includes article submissions about Nevada history as well as a small amount of correspondence to Stanley Paher, the editor of the book.

The UNLV Libraries Collection on Casino Game Protection includes resources on casino security dating from 1975 to 2004 compiled by the University of Nevada, Las Vegas Special Collections and Archives. Materials include published reports related to casino security, gaming legislation, and gaming controls. It also contains information from surveillance information network reports, including the Griffin Book by Griffin Investigations, and other sources that document persons who committed offenses in casinos. The reports were designed to assist casino operators in spotting cheaters, advantage players, and scam artists.

The Nevada Nurses Association Photograph Collection (approximately 1980-1990) is comprised of seventy-six photographic slides, and six color photographic prints that depict the Nevada Nurses Association conference held at the Sahara Hotel and Casino in Las Vegas, Nevada. The collection also includes black-and-white negatives from the 1986 Legislators' brunch in Las Vegas, Nevada.

The Carolyn Merriam Collection on the Sands Hotel (1972-1998) consists primarily of Sands Hotel merchandise and ephemera, including mugs, glassware, playing cards, dice, an ashtray, and a tote bag. The collection also contains several framed photograph reproductions depicting Las Vegas, Nevada in the 1950s and 1960s. The Sands Hotel operated in Las Vegas, Nevada from 1952 to 1996.