The Yucca Mountain Environmental Safety Collection (1970-2011) consists of reports and impact studies collected by Clark County's Nuclear Waste Division library for documenting Yucca Mountain's potential health and safety risks to Southern Nevada. The reports contain documents pertaining to potential environmental, health, financial, and safety risks from the Yucca Mountain Nuclear Waste Repository, which is located in Nye County, Nevada. The collection contains scientific and social studies in support of and opposition to the site. The bulk of the collection includes licensing reports, site selection studies, and impact studies from transporting, storing, and handling radioactive waste and spent nuclear fuel.

The collection is comprised of architectural drawings (1952-1997) completed by American architect, Ethan Jennings Jr. and/or his architectural firm, Ethan Jennings Jr., AIA, CSI and includes Jenning's work from the firm of John Badgley, AIA, where Ethan Jennings Jr. worked in Southern California during the 1950s, as well as work Jenning's completed with Americo Inc., and Tolosa Group. The collection contains 217 sets of drawings, 6 boxes of project records, and 8 flat files of oversized material from over 200 different projects primarily located in California with some projects located in the Las Vegas area. The materials feature hand-drawn architectural drawings, ranging from preliminary sketches to construction documents. The drawings also contain work from consultants, engineers, and other architects who collaborated on the development of the various projects. The drawings include: commercial, industrial, professional, civic, residential, and religious buildings of varying scales, such as libraries, apartments, warehouses, office developments, schools, military buildings, churches, and custom single-family homes located throughout California and Las Vegas. The drawings also include a number of additions, remodels, and renovations. The collection also contains project records like structural calculations and drawings, project manuals and specifications, bid documents, and professional correspondence.

The Tobias Mattstedt Menu Collection (approximately 1990-2009) is comprised of menus documenting the restaurant industry in Las Vegas, Nevada, the United States, and internationally. The menus include restaurants located in Las Vegas casinos, most notably the MGM Grand, located in Las Vegas. Included in the MGM Grand menus are restaurants such as the Pearl, Tabu Ultra Lounge, and the Grand Wok and Sushi Bar. The collection also documents menus collected by Mattstedt that are not affiliated with the MGM Corporation. These include menus located in the United States, especially Hawaii, including menus from the restaurants Olio!, Nob Hill, Diego's, and Sea Blue. The collection also includes international menus with a focus on Asian countries. The material provides insight into menu design, food culture, and the Las Vegas service industry.

Minsky's Burlesque Records (1922-1978) contain scripts, publicity, photographs, financial records, payroll records, sheet music, newspaper clippings, contracts, and correspondence. Also included are the personal papers of noted burlesque producer Harold Minsky, who was known for creating the "family burlesque" style of entertainment and for introducing the topless showgirl to Las Vegas, Nevada at the Dunes Hotel in 1957.

The Sister Klaryta Antoszewska Photograph Collection (1977-1991) consists of photographic slides that depict various Nevada, United States, and international nuclear test protests. The collection includes images of Sister Klaryta Antoszewska and Sister Rosemary Lynch, as well as images of the Lenten Desert Experience and numerous protests at the Nevada Test Site. Also included are images of nuclear testing, soldiers, and anti-nuclear testing promotional materials.

The Gay and Lesbian Community Center of Southern Nevada Photograph Collection contains mainly candid photographs of events and individuals affiliated with the Las Vegas-based Gay and Lesbian Community Center of Southern Nevada (GLCCSN) dating from 1993 to 2000. Photographs depict events honoring prominent members of the gay, lesbian, bisexual, transgender, and queer community; meetings at GLCCSN; and candidate nights for members of the community running for public office. The collection also includes a number of photographs of the Freedom to Marry celebration at the GLCCSN and the Gay Pride Las Vegas festival from 1998 to 1999.

The William S. Park Photograph Collection (approximately 1870-1960) consists of black-and-white photographic prints and negatives of the families of William S. Park, John S. Park, and John William Park, as well as photographs of the Thomas children, half-siblings of John William Park's daughter Virginia. The majority of the images show locations in Las Vegas, Nevada with a smaller number taken in Kentucky, Oklahoma, Colorado, and California. Also included are three photograph albums of William S. and John William Park as children.